Metagenomic-based pathogen surveillance for children with severe pneumonia in pediatric intensive care unit

Metagenomic-based pathogen surveillance for children with severe pneumonia in pediatric intensive care unit

BackgroundPneumonia is a significant cause of morbidity and mortality in children. Metagenomic next-generation sequencing (mNGS) has the potential to assess the landscape of pathogens responsible for severe pulmonary infection.MethodsBronchoalveolar lavage fluid (BALF) samples of 262 children with s...

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Bibliographic Details
Main Authors: Meijin Li, Jing Wang, Zhongwei Yao, Hailing Liao, Shufen Su, Xuying Yang, Mingzhou Xie, Yinan Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Public Health
Subjects:
severe pneumonia
PICU
mNGS
pathogens
co-infection
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2023.1177069/full

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