Anti-Inflammatory Effects of Miyako <i>Bidens pilosa</i> in a Mouse Model of Amyotrophic Lateral Sclerosis and Lipopolysaccharide-Stimulated BV-2 Microglia

Anti-Inflammatory Effects of Miyako <i>Bidens pilosa</i> in a Mouse Model of Amyotrophic Lateral Sclerosis and Lipopolysaccharide-Stimulated BV-2 Microglia

Neuroinflammation is a fundamental feature in the pathogenesis of amyotrophic lateral sclerosis (ALS) and arises from the activation of astrocytes and microglial cells. Previously, we reported that Miyako <i>Bidens pilosa</i> extract (MBP) inhibited microglial activation and prolonged th...

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Bibliographic Details
Main Authors: Komugi Tsuruta, Takato Shidara, Hiroko Miyagishi, Hiroshi Nango, Yoshihiko Nakatani, Naoto Suzuki, Taku Amano, Toyofumi Suzuki, Yasuhiro Kosuge
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
amyotrophic lateral sclerosis
<i>Bidens pilosa</i>
pro-inflammatory cytokines
spinal cord
M1-microglia/macrophages
Online Access:https://www.mdpi.com/1422-0067/24/18/13698

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