Technical design and concept of a 0.35 T MR-Linac

The integration of magnetic resonance (MR) imaging and linear accelerators into hybrid treatment systems has made MR-guided radiation therapy a clinical reality. This work summarizes the technical design of a 0.35 T MR-Linac and corresponding clinical concepts. The system facilitates 3D-conformal as...

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Main Author: Sebastian Klüter
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Clinical and Translational Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630819300692
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author Sebastian Klüter
author_facet Sebastian Klüter
author_sort Sebastian Klüter
collection DOAJ
description The integration of magnetic resonance (MR) imaging and linear accelerators into hybrid treatment systems has made MR-guided radiation therapy a clinical reality. This work summarizes the technical design of a 0.35 T MR-Linac and corresponding clinical concepts. The system facilitates 3D-conformal as well as IMRT treatments with 6MV photons. Daily MR imaging provides superior soft-tissue contrast for patient setup and also enables on-table adaption of treatment plans, which is fully integrated into the treatment workflow of the system. Automated beam gating during delivery is facilitated by cine MR imaging and structure tracking. Combining different novel features compared to conventional image-guided radiotherapy, this technology offers the potential for margin reduction as well as dose escalation.
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spelling doaj.art-61a5d436420a4f1cbaf20e0ed8cfee322022-12-21T20:05:00ZengElsevierClinical and Translational Radiation Oncology2405-63082019-09-011898101Technical design and concept of a 0.35 T MR-LinacSebastian Klüter0Department of Radiation Oncology, University Hospital Heidelberg, Heidelberg Institute for Radiation Oncology (HIRO), National Center for Radiation Research in Oncology (NCRO), Heidelberg, GermanyThe integration of magnetic resonance (MR) imaging and linear accelerators into hybrid treatment systems has made MR-guided radiation therapy a clinical reality. This work summarizes the technical design of a 0.35 T MR-Linac and corresponding clinical concepts. The system facilitates 3D-conformal as well as IMRT treatments with 6MV photons. Daily MR imaging provides superior soft-tissue contrast for patient setup and also enables on-table adaption of treatment plans, which is fully integrated into the treatment workflow of the system. Automated beam gating during delivery is facilitated by cine MR imaging and structure tracking. Combining different novel features compared to conventional image-guided radiotherapy, this technology offers the potential for margin reduction as well as dose escalation.http://www.sciencedirect.com/science/article/pii/S2405630819300692
spellingShingle Sebastian Klüter
Technical design and concept of a 0.35 T MR-Linac
Clinical and Translational Radiation Oncology
title Technical design and concept of a 0.35 T MR-Linac
title_full Technical design and concept of a 0.35 T MR-Linac
title_fullStr Technical design and concept of a 0.35 T MR-Linac
title_full_unstemmed Technical design and concept of a 0.35 T MR-Linac
title_short Technical design and concept of a 0.35 T MR-Linac
title_sort technical design and concept of a 0 35 t mr linac
url http://www.sciencedirect.com/science/article/pii/S2405630819300692
work_keys_str_mv AT sebastiankluter technicaldesignandconceptofa035tmrlinac