Oral lichen planus and HCV infection

Chronic infection by hepatitis C virus (HCV) can lead not only to the development of hepatic cirrhosis, but also to the emergence of extra-hepatic manifestations (EHMs), such as oral lichen planus (OLP). Here, we describe a clinical presentation of massive, erosive OLP in an HCV-positive patient who...

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Main Authors: Jefferson R. Tenório, Alessandra Rodrigues de Camargo, Celso Lemos, Karem L. Ortega
Format: Article
Language:English
Published: University of São Paulo 2021-08-01
Series:Autopsy and Case Reports
Subjects:
Online Access:https://www.revistas.usp.br/autopsy/article/view/188453
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author Jefferson R. Tenório
Alessandra Rodrigues de Camargo
Celso Lemos
Karem L. Ortega
author_facet Jefferson R. Tenório
Alessandra Rodrigues de Camargo
Celso Lemos
Karem L. Ortega
author_sort Jefferson R. Tenório
collection DOAJ
description Chronic infection by hepatitis C virus (HCV) can lead not only to the development of hepatic cirrhosis, but also to the emergence of extra-hepatic manifestations (EHMs), such as oral lichen planus (OLP). Here, we describe a clinical presentation of massive, erosive OLP in an HCV-positive patient whose clinical management was difficult. Full remission was achieved after sustained virological response by using direct-acting anti-retrovirals. This case report demonstrates not only the importance of diagnosing EHMs for identification of HCV infection, but also the importance of controlling it for management of OLP and EHMs.
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spelling doaj.art-61ac9285dac849d2970bb97f018543982022-12-21T23:50:40ZengUniversity of São PauloAutopsy and Case Reports2236-19602021-08-01104Oral lichen planus and HCV infectionJefferson R. Tenório0Alessandra Rodrigues de Camargo1Celso Lemos2Karem L. Ortega3Universidade de São Paulo (USP), Faculdade de Odontologia, Patologia Oral e Maxilofacial, Departamento de Estomatologia, São Paulo, SP, Brasil Universidade Federal de Santa Catarina (UFSC), Departamento de Estomatologia, Florianópolis, SC, Brasil Universidade de São Paulo (USP), Faculdade de Odontologia, Departamento de Estomatologia, São Paulo, SP, BrasilUniversidade de São Paulo (USP), Faculdade de Odontologia, Patologia Oral e Maxilofacial, Departamento de Estomatologia, São Paulo, SP, BrasilChronic infection by hepatitis C virus (HCV) can lead not only to the development of hepatic cirrhosis, but also to the emergence of extra-hepatic manifestations (EHMs), such as oral lichen planus (OLP). Here, we describe a clinical presentation of massive, erosive OLP in an HCV-positive patient whose clinical management was difficult. Full remission was achieved after sustained virological response by using direct-acting anti-retrovirals. This case report demonstrates not only the importance of diagnosing EHMs for identification of HCV infection, but also the importance of controlling it for management of OLP and EHMs.https://www.revistas.usp.br/autopsy/article/view/188453Hepatitis CChronicLichen Planus, Oral
spellingShingle Jefferson R. Tenório
Alessandra Rodrigues de Camargo
Celso Lemos
Karem L. Ortega
Oral lichen planus and HCV infection
Autopsy and Case Reports
Hepatitis C
Chronic
Lichen Planus, Oral
title Oral lichen planus and HCV infection
title_full Oral lichen planus and HCV infection
title_fullStr Oral lichen planus and HCV infection
title_full_unstemmed Oral lichen planus and HCV infection
title_short Oral lichen planus and HCV infection
title_sort oral lichen planus and hcv infection
topic Hepatitis C
Chronic
Lichen Planus, Oral
url https://www.revistas.usp.br/autopsy/article/view/188453
work_keys_str_mv AT jeffersonrtenorio orallichenplanusandhcvinfection
AT alessandrarodriguesdecamargo orallichenplanusandhcvinfection
AT celsolemos orallichenplanusandhcvinfection
AT karemlortega orallichenplanusandhcvinfection