DNA-Based Gold Nanoparticle Assemblies: From Structure Constructions to Sensing Applications
Gold nanoparticles (Au NPs) have become one of the building blocks for superior assembly and device fabrication due to the intrinsic, tunable physical properties of nanoparticles. With the development of DNA nanotechnology, gold nanoparticles are organized in a highly precise and controllable way un...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
|
| Series: | Sensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8220/23/22/9229 |
| _version_ | 1827638761769402368 |
|---|---|
| author | Mo Xie Jinke Jiang Jie Chao |
| author_facet | Mo Xie Jinke Jiang Jie Chao |
| author_sort | Mo Xie |
| collection | DOAJ |
| description | Gold nanoparticles (Au NPs) have become one of the building blocks for superior assembly and device fabrication due to the intrinsic, tunable physical properties of nanoparticles. With the development of DNA nanotechnology, gold nanoparticles are organized in a highly precise and controllable way under the mediation of DNA, achieving programmability and specificity unmatched by other ligands. The successful construction of abundant gold nanoparticle assembly structures has also given rise to the fabrication of a wide range of sensors, which has greatly contributed to the development of the sensing field. In this review, we focus on the progress in the DNA-mediated assembly of Au NPs and their application in sensing in the past five years. Firstly, we highlight the strategies used for the orderly organization of Au NPs with DNA. Then, we describe the DNA-based assembly of Au NPs for sensing applications and representative research therein. Finally, we summarize the advantages of DNA nanotechnology in assembling complex Au NPs and outline the challenges and limitations in constructing complex gold nanoparticle assembly structures with tailored functionalities. |
| first_indexed | 2024-03-09T16:27:25Z |
| format | Article |
| id | doaj.art-61b3be34144c497ab0a0a7b217813e75 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-09T16:27:25Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-61b3be34144c497ab0a0a7b217813e752023-11-24T15:05:50ZengMDPI AGSensors1424-82202023-11-012322922910.3390/s23229229DNA-Based Gold Nanoparticle Assemblies: From Structure Constructions to Sensing ApplicationsMo Xie0Jinke Jiang1Jie Chao2State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, ChinaState Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, ChinaState Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, ChinaGold nanoparticles (Au NPs) have become one of the building blocks for superior assembly and device fabrication due to the intrinsic, tunable physical properties of nanoparticles. With the development of DNA nanotechnology, gold nanoparticles are organized in a highly precise and controllable way under the mediation of DNA, achieving programmability and specificity unmatched by other ligands. The successful construction of abundant gold nanoparticle assembly structures has also given rise to the fabrication of a wide range of sensors, which has greatly contributed to the development of the sensing field. In this review, we focus on the progress in the DNA-mediated assembly of Au NPs and their application in sensing in the past five years. Firstly, we highlight the strategies used for the orderly organization of Au NPs with DNA. Then, we describe the DNA-based assembly of Au NPs for sensing applications and representative research therein. Finally, we summarize the advantages of DNA nanotechnology in assembling complex Au NPs and outline the challenges and limitations in constructing complex gold nanoparticle assembly structures with tailored functionalities.https://www.mdpi.com/1424-8220/23/22/9229DNA strandsDNA nanostructuresgold nanoparticleplasmonicsensing |
| spellingShingle | Mo Xie Jinke Jiang Jie Chao DNA-Based Gold Nanoparticle Assemblies: From Structure Constructions to Sensing Applications Sensors DNA strands DNA nanostructures gold nanoparticle plasmonic sensing |
| title | DNA-Based Gold Nanoparticle Assemblies: From Structure Constructions to Sensing Applications |
| title_full | DNA-Based Gold Nanoparticle Assemblies: From Structure Constructions to Sensing Applications |
| title_fullStr | DNA-Based Gold Nanoparticle Assemblies: From Structure Constructions to Sensing Applications |
| title_full_unstemmed | DNA-Based Gold Nanoparticle Assemblies: From Structure Constructions to Sensing Applications |
| title_short | DNA-Based Gold Nanoparticle Assemblies: From Structure Constructions to Sensing Applications |
| title_sort | dna based gold nanoparticle assemblies from structure constructions to sensing applications |
| topic | DNA strands DNA nanostructures gold nanoparticle plasmonic sensing |
| url | https://www.mdpi.com/1424-8220/23/22/9229 |
| work_keys_str_mv | AT moxie dnabasedgoldnanoparticleassembliesfromstructureconstructionstosensingapplications AT jinkejiang dnabasedgoldnanoparticleassembliesfromstructureconstructionstosensingapplications AT jiechao dnabasedgoldnanoparticleassembliesfromstructureconstructionstosensingapplications |