Breast involvement in mixed connective tissue disease
To date, mammographic involvement in mixed connective tissue disease has not been described in the literature to the authors’ knowledge. In addition, only 2 case reports have described panniculitis in mixed connective tissue disease. We present a patient with mixed connective tissue disease with coa...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-04-01
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| Series: | Radiology Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S193004331730465X |
| _version_ | 1819200036851941376 |
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| author | Ross Varma, MD Sandor Szilagyi, MD Manju Harshan, MD |
| author_facet | Ross Varma, MD Sandor Szilagyi, MD Manju Harshan, MD |
| author_sort | Ross Varma, MD |
| collection | DOAJ |
| description | To date, mammographic involvement in mixed connective tissue disease has not been described in the literature to the authors’ knowledge. In addition, only 2 case reports have described panniculitis in mixed connective tissue disease. We present a patient with mixed connective tissue disease with coarse sheet-like calcifications on mammography bilaterally, which increased over time corresponding to rise in levels of anti-dsDNA. Biopsy showed fat necrosis with calcifications, chronic inflammation and fibrosis, vasculitis, as well as CD3, CD4, and CD8+ T cells and CD20+ B cells. These findings are similar histologically and mammographically to “lupus mastitis.” Keywords: MCTD, Mixed connective tissue disease, Mastitis, Lupus mastitis, MCTD panniculitis, Mammography |
| first_indexed | 2024-12-23T03:25:51Z |
| format | Article |
| id | doaj.art-61b4f1128cc84aaabe0972e791ab061e |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-23T03:25:51Z |
| publishDate | 2019-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-61b4f1128cc84aaabe0972e791ab061e2022-12-21T18:01:51ZengElsevierRadiology Case Reports1930-04332019-04-01144430435Breast involvement in mixed connective tissue diseaseRoss Varma, MD0Sandor Szilagyi, MD1Manju Harshan, MD2Department of Radiology, Mount Sinai West, 1000 Tenth Avenue, NY 10019, New York, USA; Corresponding author.Department of Radiology, Mount Sinai Beth Israel, 10 Nathan D Perlman Pl, NY 10003, New York, USADepartment of Pathology, Mount Sinai Downtown Union Square. 10 Union Square East, NY 10003, New York, USATo date, mammographic involvement in mixed connective tissue disease has not been described in the literature to the authors’ knowledge. In addition, only 2 case reports have described panniculitis in mixed connective tissue disease. We present a patient with mixed connective tissue disease with coarse sheet-like calcifications on mammography bilaterally, which increased over time corresponding to rise in levels of anti-dsDNA. Biopsy showed fat necrosis with calcifications, chronic inflammation and fibrosis, vasculitis, as well as CD3, CD4, and CD8+ T cells and CD20+ B cells. These findings are similar histologically and mammographically to “lupus mastitis.” Keywords: MCTD, Mixed connective tissue disease, Mastitis, Lupus mastitis, MCTD panniculitis, Mammographyhttp://www.sciencedirect.com/science/article/pii/S193004331730465X |
| spellingShingle | Ross Varma, MD Sandor Szilagyi, MD Manju Harshan, MD Breast involvement in mixed connective tissue disease Radiology Case Reports |
| title | Breast involvement in mixed connective tissue disease |
| title_full | Breast involvement in mixed connective tissue disease |
| title_fullStr | Breast involvement in mixed connective tissue disease |
| title_full_unstemmed | Breast involvement in mixed connective tissue disease |
| title_short | Breast involvement in mixed connective tissue disease |
| title_sort | breast involvement in mixed connective tissue disease |
| url | http://www.sciencedirect.com/science/article/pii/S193004331730465X |
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