NRF2 is essential for adaptative browning of white adipocytes

NRF2 is essential for adaptative browning of white adipocytes

White adipose tissue browning, defined by accelerated mitochondrial metabolism and biogenesis, is considered a promising mean to treat or prevent obesity-associated metabolic disturbances. We hypothesize that redox stress acutely leads to increased production of reactive oxygen species (ROS), which...

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Bibliographic Details
Main Authors: Marco Bauzá-Thorbrügge, Eduard Peris, Shabnam Zamani, Peter Micallef, Alexandra Paul, Stefano Bartesaghi, Anna Benrick, Ingrid Wernstedt Asterholm
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Redox Biology
Subjects:
Adipose tissue
Redox stress
NRF2
N-acetylcysteine
Lactate
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172300352X

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