Transient up-regulation of miR-155-3p by lipopolysaccharide in primary human monocyte-derived macrophages results in RISC incorporation but does not alter TNF expression [version 2; peer review: 1 approved, 2 approved with reservations]
Background: The innate immune response is a tightly regulated process that reacts rapidly in response to pathogen-associated molecular patterns (PAMPs) such as lipopolysaccharide (LPS). Evidence is accumulating that microRNAs contribute to this, although few studies have examined the early events th...
Main Author: | Rachel E. Simmonds |
---|---|
Format: | Article |
Language: | English |
Published: |
Wellcome
2019-10-01
|
Series: | Wellcome Open Research |
Online Access: | https://wellcomeopenresearch.org/articles/4-43/v2 |
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