Transient up-regulation of miR-155-3p by lipopolysaccharide in primary human monocyte-derived macrophages results in RISC incorporation but does not alter TNF expression [version 2; peer review: 1 approved, 2 approved with reservations]

Background: The innate immune response is a tightly regulated process that reacts rapidly in response to pathogen-associated molecular patterns (PAMPs) such as lipopolysaccharide (LPS). Evidence is accumulating that microRNAs contribute to this, although few studies have examined the early events th...

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Bibliographic Details
Main Author: Rachel E. Simmonds
Format: Article
Language:English
Published: Wellcome 2019-10-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/4-43/v2

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