The complex issue of medication management in older persons: a challenge for nurses

With increasing life expectancy, the share of older persons with coexisting multiple chronic degenerative diseases (comorbidity / multimorbidity) is expanding. These conditions require the use of multiple drugs, leading to polypharmacy, which plays a central role in making the therapeutic approach t...

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Main Authors: Carmen Maria Vitiello, Yari Longobucco, Sofia Espinoza Tofalos, Mauro Di Bari
Format: Article
Language:English
Published: Firenze University Press 2022-06-01
Series:Infermieristica Journal
Subjects:
Online Access:https://riviste.fupress.net/index.php/if/article/view/1714
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author Carmen Maria Vitiello
Yari Longobucco
Sofia Espinoza Tofalos
Mauro Di Bari
author_facet Carmen Maria Vitiello
Yari Longobucco
Sofia Espinoza Tofalos
Mauro Di Bari
author_sort Carmen Maria Vitiello
collection DOAJ
description With increasing life expectancy, the share of older persons with coexisting multiple chronic degenerative diseases (comorbidity / multimorbidity) is expanding. These conditions require the use of multiple drugs, leading to polypharmacy, which plays a central role in making the therapeutic approach to the elderly particularly complex, together with age-related changes in pharmacokinetics and pharmacodynamics. Physicians and nurses both are challenged by polypharmacy and by the other drug-related issues involving older patients, in all care settings. In particular, nurses should be aware of the main issues of pharmacotherapy in older persons, because they are often the frontline for older patients care, especially in nursing homes. This review addresses the main issues related to pharmacotherapy in late life, such as pharmacokinetics and pharmacodynamics changes, limitations of evidence-based medicine, polypharmacy, drug interactions, adverse drug reactions, and lack of adherence. Focus will be on how these problems may impact on nursing, and on what nurses should know and do to improve drug treatment of older patients. In the last decade, the role and responsibilities of nurses in the management of drug therapy have significantly changed in most countries. There is consensus in educational programs and legislation that the preparation and administration of medications are essential aspects of nursing practice. These are considered as collaborative tasks with physicians and not purely mechanistic tasks. The nurse must intervene in the event of a perceived error, and he/she must report doubts about congruity or relevance of the therapy. Although nursing students gain knowledge and develop skills on drug therapy during their education, these are often perceived as insufficient. The need for post-graduation continuing education should be also emphasized. Thus, graduate and post-graduate educational programs should be developed, in order to offer adequate answers to the increasing and challenging share of older patients seen in clinical practice.
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spelling doaj.art-61bd6833ab384fb093817cfbb08fdcb82024-04-17T15:01:44ZengFirenze University PressInfermieristica Journal2785-70182022-06-0111495610.36253/if-17141541The complex issue of medication management in older persons: a challenge for nursesCarmen Maria Vitiello0Yari Longobucco1Sofia Espinoza Tofalos2Mauro Di Bari3RN, Department of Experimental and Clinical Medicine, University of Florence, Florence, ItalyRN, PhD, Department of Experimental and Clinical Medicine, University of Florence, Florence, ItalyMD, Department of Experimental and Clinical Medicine, University of Florence, Florence, ItalyAssociate professor, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Unit of Geriatrics, Department of Medicine and Geriatrics, Azienda Ospedaliero-Universitaria Careggi, Florence, ItalyWith increasing life expectancy, the share of older persons with coexisting multiple chronic degenerative diseases (comorbidity / multimorbidity) is expanding. These conditions require the use of multiple drugs, leading to polypharmacy, which plays a central role in making the therapeutic approach to the elderly particularly complex, together with age-related changes in pharmacokinetics and pharmacodynamics. Physicians and nurses both are challenged by polypharmacy and by the other drug-related issues involving older patients, in all care settings. In particular, nurses should be aware of the main issues of pharmacotherapy in older persons, because they are often the frontline for older patients care, especially in nursing homes. This review addresses the main issues related to pharmacotherapy in late life, such as pharmacokinetics and pharmacodynamics changes, limitations of evidence-based medicine, polypharmacy, drug interactions, adverse drug reactions, and lack of adherence. Focus will be on how these problems may impact on nursing, and on what nurses should know and do to improve drug treatment of older patients. In the last decade, the role and responsibilities of nurses in the management of drug therapy have significantly changed in most countries. There is consensus in educational programs and legislation that the preparation and administration of medications are essential aspects of nursing practice. These are considered as collaborative tasks with physicians and not purely mechanistic tasks. The nurse must intervene in the event of a perceived error, and he/she must report doubts about congruity or relevance of the therapy. Although nursing students gain knowledge and develop skills on drug therapy during their education, these are often perceived as insufficient. The need for post-graduation continuing education should be also emphasized. Thus, graduate and post-graduate educational programs should be developed, in order to offer adequate answers to the increasing and challenging share of older patients seen in clinical practice.https://riviste.fupress.net/index.php/if/article/view/1714elderlypolypharmacynurse skillsnurse competencestherapeutic adherenceadverse drug reaction
spellingShingle Carmen Maria Vitiello
Yari Longobucco
Sofia Espinoza Tofalos
Mauro Di Bari
The complex issue of medication management in older persons: a challenge for nurses
Infermieristica Journal
elderly
polypharmacy
nurse skills
nurse competences
therapeutic adherence
adverse drug reaction
title The complex issue of medication management in older persons: a challenge for nurses
title_full The complex issue of medication management in older persons: a challenge for nurses
title_fullStr The complex issue of medication management in older persons: a challenge for nurses
title_full_unstemmed The complex issue of medication management in older persons: a challenge for nurses
title_short The complex issue of medication management in older persons: a challenge for nurses
title_sort complex issue of medication management in older persons a challenge for nurses
topic elderly
polypharmacy
nurse skills
nurse competences
therapeutic adherence
adverse drug reaction
url https://riviste.fupress.net/index.php/if/article/view/1714
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