Clinical cases of extrapulmonary manifestations in patients with coronavirus disease (COVID-19)

The aim of the work – to provide variants of extrapulmonary manifestations of coronavirus disease (COVID-19) based on the analysis of the relevant course of the disease in adults. Results. The paper presents two clinical cases of coronavirus disease (COVID-19) with the manifestation of extrapulmo...

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Main Authors: O. V. Riabokon, К. А. Pak, О. О. Furyk, V. V. Cherkaskyi
Format: Article
Language:English
Published: Zaporozhye State Medical University 2022-10-01
Series:Patologìâ
Subjects:
Online Access:http://pat.zsmu.edu.ua/article/view/257403/261867
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author O. V. Riabokon
К. А. Pak
О. О. Furyk
V. V. Cherkaskyi
author_facet O. V. Riabokon
К. А. Pak
О. О. Furyk
V. V. Cherkaskyi
author_sort O. V. Riabokon
collection DOAJ
description The aim of the work – to provide variants of extrapulmonary manifestations of coronavirus disease (COVID-19) based on the analysis of the relevant course of the disease in adults. Results. The paper presents two clinical cases of coronavirus disease (COVID-19) with the manifestation of extrapulmonary symptoms, which required some individualization of therapy. The first clinical observation showed that in a 56-year-old patient with moderate COVID-19, the development of oxygen dependence on the 8th day of the disease was combined with the manifestation of extrapulmonary symptoms in the form of cutaneous manifestations. Individualization of glucocorticosteroid therapy and endothelioprotective therapy has been shown to be effective in regressing both oxygen dependence and cutaneous vasculitis. The second clinical observation showed that in a 35-year-old patient, moderate COVID-19 without oxygen dependence was accompanied by the development of extrapulmonary manifestations, namely short-lasting diarrheal syndrome, which manifested in the onset of the disease and of the development of orchiepididymitis on the 9th day of illness, which required the appointment of anti-inflammatory therapy. Conclusions. The abovementioned clinical observations of COVID-19 cases show relatively rare cases of SARS-CoV-2- associated extrapulmonary manifestations in patients with moderate disease, but their development necessitated individualization of treatment.
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spelling doaj.art-61bf375269f544d98fe6ec4df04435b72022-12-22T03:53:32ZengZaporozhye State Medical UniversityPatologìâ2306-80272310-12372022-10-0119216016510.14739/2310-1237.2022.2.257403Clinical cases of extrapulmonary manifestations in patients with coronavirus disease (COVID-19)O. V. Riabokon0https://orcid.org/0000-0002-7394-4649К. А. Pak1https://orcid.org/0000-0002-2286-6919О. О. Furyk2https://orcid.org/0000-0002-5196-7698V. V. Cherkaskyi3https://orcid.org/0000-0003-2959-8803Zaporizhzhia State Medical University, UkraineZaporizhzhia State Medical University, UkraineZaporizhzhia State Medical University, UkraineZaporizhzhia State Medical University, UkraineThe aim of the work – to provide variants of extrapulmonary manifestations of coronavirus disease (COVID-19) based on the analysis of the relevant course of the disease in adults. Results. The paper presents two clinical cases of coronavirus disease (COVID-19) with the manifestation of extrapulmonary symptoms, which required some individualization of therapy. The first clinical observation showed that in a 56-year-old patient with moderate COVID-19, the development of oxygen dependence on the 8th day of the disease was combined with the manifestation of extrapulmonary symptoms in the form of cutaneous manifestations. Individualization of glucocorticosteroid therapy and endothelioprotective therapy has been shown to be effective in regressing both oxygen dependence and cutaneous vasculitis. The second clinical observation showed that in a 35-year-old patient, moderate COVID-19 without oxygen dependence was accompanied by the development of extrapulmonary manifestations, namely short-lasting diarrheal syndrome, which manifested in the onset of the disease and of the development of orchiepididymitis on the 9th day of illness, which required the appointment of anti-inflammatory therapy. Conclusions. The abovementioned clinical observations of COVID-19 cases show relatively rare cases of SARS-CoV-2- associated extrapulmonary manifestations in patients with moderate disease, but their development necessitated individualization of treatment. http://pat.zsmu.edu.ua/article/view/257403/261867coronavirus disease covid-19viral infectionextrapulmonary manifestationstreatment
spellingShingle O. V. Riabokon
К. А. Pak
О. О. Furyk
V. V. Cherkaskyi
Clinical cases of extrapulmonary manifestations in patients with coronavirus disease (COVID-19)
Patologìâ
coronavirus disease covid-19
viral infection
extrapulmonary manifestations
treatment
title Clinical cases of extrapulmonary manifestations in patients with coronavirus disease (COVID-19)
title_full Clinical cases of extrapulmonary manifestations in patients with coronavirus disease (COVID-19)
title_fullStr Clinical cases of extrapulmonary manifestations in patients with coronavirus disease (COVID-19)
title_full_unstemmed Clinical cases of extrapulmonary manifestations in patients with coronavirus disease (COVID-19)
title_short Clinical cases of extrapulmonary manifestations in patients with coronavirus disease (COVID-19)
title_sort clinical cases of extrapulmonary manifestations in patients with coronavirus disease covid 19
topic coronavirus disease covid-19
viral infection
extrapulmonary manifestations
treatment
url http://pat.zsmu.edu.ua/article/view/257403/261867
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AT kapak clinicalcasesofextrapulmonarymanifestationsinpatientswithcoronavirusdiseasecovid19
AT oofuryk clinicalcasesofextrapulmonarymanifestationsinpatientswithcoronavirusdiseasecovid19
AT vvcherkaskyi clinicalcasesofextrapulmonarymanifestationsinpatientswithcoronavirusdiseasecovid19