Proinflammatory cytokines and lipopolysaccharides up regulate MMP-3 and MMP-13 production in Asian elephant (Elephas maximus) chondrocytes: attenuation by anti-arthritic agents

Proinflammatory cytokines and lipopolysaccharides up regulate MMP-3 and MMP-13 production in Asian elephant (Elephas maximus) chondrocytes: attenuation by anti-arthritic agents

Abstract Background Osteoarthritis (OA), the most common form of arthritic disease, results from destruction of joint cartilage and underlying bone. It affects animals, including Asian elephants (Elephas maximus) in captivity, leading to joint pain and lameness. However, publications regarding OA pa...

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Bibliographic Details
Main Authors: Nutnicha Sirikaew, Siriwadee Chomdej, Siriwan Tangyuenyong, Weerapongse Tangjitjaroen, Chaleamchat Somgird, Chatchote Thitaram, Siriwan Ongchai
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Veterinary Research
Subjects:
Elephas maximus
Osteoarthritis
Proinflammatory cytokines
MMP-3
MMP-13
Online Access:http://link.springer.com/article/10.1186/s12917-019-2170-8

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