Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia

To comprehensively reflect the roles of Rpl11 on the transcriptome of zebrafish model of Diamond-Blackfan Anemia (DBA), we performed whole-genome transcriptome sequencing on the Illumina Hi-Seq 2000 sequencing platform. Two different transcriptomes of zebrafish Rpl11-deficient and control Morpholino...

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Main Authors: Zhaojun Zhang, Haibo Jia, Qian Zhang, Yang Wan, Binfeng Song, Qiong Jia, Hanzhi Liu, Xiaofan Zhu, Xiangdong Fang
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Genomics Data
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596014000415
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author Zhaojun Zhang
Haibo Jia
Qian Zhang
Yang Wan
Binfeng Song
Qiong Jia
Hanzhi Liu
Xiaofan Zhu
Xiangdong Fang
author_facet Zhaojun Zhang
Haibo Jia
Qian Zhang
Yang Wan
Binfeng Song
Qiong Jia
Hanzhi Liu
Xiaofan Zhu
Xiangdong Fang
author_sort Zhaojun Zhang
collection DOAJ
description To comprehensively reflect the roles of Rpl11 on the transcriptome of zebrafish model of Diamond-Blackfan Anemia (DBA), we performed whole-genome transcriptome sequencing on the Illumina Hi-Seq 2000 sequencing platform. Two different transcriptomes of zebrafish Rpl11-deficient and control Morpholino (Mo) embryos were collected and analyzed. The experimental design and methods, including sample preparation, RNA-Seq data evaluation and treatment, were described in details so that representative high-throughput sequencing data were acquired for assessing the actual impacts of Rpl11 on zebrafish embryos. We provided the accession number GSE51326 for easy access to the database.
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spelling doaj.art-61c0fc63fdfa4e7faca4c47f075afabc2022-12-22T00:27:16ZengElsevierGenomics Data2213-59602014-12-012C17317510.1016/j.gdata.2014.06.008Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan AnemiaZhaojun Zhang0Haibo Jia1Qian Zhang2Yang Wan3Binfeng Song4Qiong Jia5Hanzhi Liu6Xiaofan Zhu7Xiangdong Fang8CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, ChinaKey Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei 430074, ChinaCAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, ChinaState Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, ChinaKey Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei 430074, ChinaKey Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei 430074, ChinaState Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, ChinaState Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, ChinaCAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, ChinaTo comprehensively reflect the roles of Rpl11 on the transcriptome of zebrafish model of Diamond-Blackfan Anemia (DBA), we performed whole-genome transcriptome sequencing on the Illumina Hi-Seq 2000 sequencing platform. Two different transcriptomes of zebrafish Rpl11-deficient and control Morpholino (Mo) embryos were collected and analyzed. The experimental design and methods, including sample preparation, RNA-Seq data evaluation and treatment, were described in details so that representative high-throughput sequencing data were acquired for assessing the actual impacts of Rpl11 on zebrafish embryos. We provided the accession number GSE51326 for easy access to the database.http://www.sciencedirect.com/science/article/pii/S2213596014000415TranscriptomeZebrafishDBAHigh-Seq 2000IPA
spellingShingle Zhaojun Zhang
Haibo Jia
Qian Zhang
Yang Wan
Binfeng Song
Qiong Jia
Hanzhi Liu
Xiaofan Zhu
Xiangdong Fang
Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia
Genomics Data
Transcriptome
Zebrafish
DBA
High-Seq 2000
IPA
title Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia
title_full Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia
title_fullStr Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia
title_full_unstemmed Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia
title_short Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia
title_sort transcriptome analysis of rpl11 deficient zebrafish model of diamond blackfan anemia
topic Transcriptome
Zebrafish
DBA
High-Seq 2000
IPA
url http://www.sciencedirect.com/science/article/pii/S2213596014000415
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