Anaphylaxis Complicated by Acute Respiratory Distress and Fatal Outcome in A Nigerian Family

Reports on hypersensitivity diseases in Nigerians are rare. We report the incidence of anaphylaxis in three siblings following fatal outcome in their mother. Urticarial rashes were noticed in three siblings’ resident in a South Western Nigerian town, one week before presentation at our facility. A...

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Main Authors: Efeturi Agelebe, Tawakalit Lily Musa, Idowu Adebowale Ajayi, Olusola Adetunji Oyedeji
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2017-01-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/9158/21449_CE[Ra1]_F(DK)_PF1_(DK_RO)_PFA(DK)_PF2(SS_NE_DK).pdf
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author Efeturi Agelebe
Tawakalit Lily Musa
Idowu Adebowale Ajayi
Olusola Adetunji Oyedeji
author_facet Efeturi Agelebe
Tawakalit Lily Musa
Idowu Adebowale Ajayi
Olusola Adetunji Oyedeji
author_sort Efeturi Agelebe
collection DOAJ
description Reports on hypersensitivity diseases in Nigerians are rare. We report the incidence of anaphylaxis in three siblings following fatal outcome in their mother. Urticarial rashes were noticed in three siblings’ resident in a South Western Nigerian town, one week before presentation at our facility. All the three siblings developed respiratory distress four days after the rash was noticed. Onset of respiratory distress made the family seek care at a private hospital, where they were admitted and treated with intravenous aminophylline and ceftriaxone. The mother of the children had experienced the same symptoms earlier also. She took treatment and died in the same private hospital, where her children received care. Death of the mother and worsening respiratory distress in the children made the father effect transfer of the children to the paediatric emergency unit of Ladoke Akintola University of Technology Teaching Hospital, Osogbo. The three children made a slow but uneventful recovery after instituting appropriate management for anaphylaxis and acute respiratory distress syndrome. The cases are discussed with a view to create awareness amongst health practitioners about the occurrence of anaphylaxis in our society. The need for prompt recognition and appropriate management, when confronted with this disease is also underscored.
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spelling doaj.art-61c8a4460d3041a7b8d7b0a488af69aa2022-12-21T21:49:05ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-01-01111SD01SD0310.7860/JCDR/2017/21449.9158Anaphylaxis Complicated by Acute Respiratory Distress and Fatal Outcome in A Nigerian FamilyEfeturi Agelebe0Tawakalit Lily Musa1Idowu Adebowale Ajayi2Olusola Adetunji Oyedeji3Senior Registrar, Department of Paediatrics and Child Health, Ladoke Akintola University of Technology Teaching Hospital, Osogbo, Osun State, Nigeria.Senior Registrar, Department of Paediatrics and Child Health, Ladoke Akintola University of Technology, Teaching Hospital, Osogbo, Osun State, Nigeria.Consultant Radiologist, Department of Radiology, Ladoke Akintola University of Technology, Teaching Hospital, Osogbo, Osun State, Nigeria.Consultant Paediatrician, Department of Paediatrics and Child Health, Ladoke Akintola University of Technology Teaching Hospital, Osogbo, Osun State, Nigeria.Reports on hypersensitivity diseases in Nigerians are rare. We report the incidence of anaphylaxis in three siblings following fatal outcome in their mother. Urticarial rashes were noticed in three siblings’ resident in a South Western Nigerian town, one week before presentation at our facility. All the three siblings developed respiratory distress four days after the rash was noticed. Onset of respiratory distress made the family seek care at a private hospital, where they were admitted and treated with intravenous aminophylline and ceftriaxone. The mother of the children had experienced the same symptoms earlier also. She took treatment and died in the same private hospital, where her children received care. Death of the mother and worsening respiratory distress in the children made the father effect transfer of the children to the paediatric emergency unit of Ladoke Akintola University of Technology Teaching Hospital, Osogbo. The three children made a slow but uneventful recovery after instituting appropriate management for anaphylaxis and acute respiratory distress syndrome. The cases are discussed with a view to create awareness amongst health practitioners about the occurrence of anaphylaxis in our society. The need for prompt recognition and appropriate management, when confronted with this disease is also underscored.https://jcdr.net/articles/PDF/9158/21449_CE[Ra1]_F(DK)_PF1_(DK_RO)_PFA(DK)_PF2(SS_NE_DK).pdfallergicchildhooddiseases
spellingShingle Efeturi Agelebe
Tawakalit Lily Musa
Idowu Adebowale Ajayi
Olusola Adetunji Oyedeji
Anaphylaxis Complicated by Acute Respiratory Distress and Fatal Outcome in A Nigerian Family
Journal of Clinical and Diagnostic Research
allergic
childhood
diseases
title Anaphylaxis Complicated by Acute Respiratory Distress and Fatal Outcome in A Nigerian Family
title_full Anaphylaxis Complicated by Acute Respiratory Distress and Fatal Outcome in A Nigerian Family
title_fullStr Anaphylaxis Complicated by Acute Respiratory Distress and Fatal Outcome in A Nigerian Family
title_full_unstemmed Anaphylaxis Complicated by Acute Respiratory Distress and Fatal Outcome in A Nigerian Family
title_short Anaphylaxis Complicated by Acute Respiratory Distress and Fatal Outcome in A Nigerian Family
title_sort anaphylaxis complicated by acute respiratory distress and fatal outcome in a nigerian family
topic allergic
childhood
diseases
url https://jcdr.net/articles/PDF/9158/21449_CE[Ra1]_F(DK)_PF1_(DK_RO)_PFA(DK)_PF2(SS_NE_DK).pdf
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AT idowuadebowaleajayi anaphylaxiscomplicatedbyacuterespiratorydistressandfataloutcomeinanigerianfamily
AT olusolaadetunjioyedeji anaphylaxiscomplicatedbyacuterespiratorydistressandfataloutcomeinanigerianfamily