Erosive pustular dermatosis of the scalp: a pathogenetic мystery and therapeutic challenge
Erosive pustular dermatosis of the scalp (EPDS) is a rare condition which affects predominantly the adult population, and occurs on a previously photo-damaged bald scalp. The physical examination is presented with a large erythematous, erosive and crusted patches with granulation on an atrophic ski...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2022-07-01
|
| Series: | Dermatology Reports |
| Subjects: | |
| Online Access: | https://www.pagepress.org/journals/index.php/dr/article/view/9556 |
| _version_ | 1828780019137118208 |
|---|---|
| author | Georgi Tchernev Simona Kordeva Ilia Batashki Atanas Batashki Heily Kirilova Konstantin Stavrov |
| author_facet | Georgi Tchernev Simona Kordeva Ilia Batashki Atanas Batashki Heily Kirilova Konstantin Stavrov |
| author_sort | Georgi Tchernev |
| collection | DOAJ |
| description |
Erosive pustular dermatosis of the scalp (EPDS) is a rare condition which affects predominantly the adult population, and occurs on a previously photo-damaged bald scalp. The physical examination is presented with a large erythematous, erosive and crusted patches with granulation on an atrophic skin. The problem in patients with erosive pustular dermatosis of the scalp arises from the nonspecific clinical and histopathological findings, which can be misleading. Biopsy followed by careful histopathological verification is mandatory, although the finding is nonspecific.The histopathology findings are characterized by superficial erosions with mild neutrophil infiltrate, mainly intravascular and focally with neutrophil exocytosis. Focal parakeratosis, smoothed rete ridges without pronounced interface changes. Pronounced lymphoplasmacytic infiltrate with focal distribution in the dermis, giant cell reaction with the formation of a “foreign body” granuloma. We report a 58-year old male patient with a 1 year old lesion, suspected for skin cancer, later diagnosed with EPDS, which was successfully treated with topical clobetasol proprionate after 3-5 weeks.
|
| first_indexed | 2024-12-11T17:11:43Z |
| format | Article |
| id | doaj.art-61c93e2cc19e473cabb3f561d7da651f |
| institution | Directory Open Access Journal |
| issn | 2036-7392 2036-7406 |
| language | English |
| last_indexed | 2024-12-11T17:11:43Z |
| publishDate | 2022-07-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Dermatology Reports |
| spelling | doaj.art-61c93e2cc19e473cabb3f561d7da651f2022-12-22T00:57:31ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062022-07-0110.4081/dr.2022.9556Erosive pustular dermatosis of the scalp: a pathogenetic мystery and therapeutic challengeGeorgi Tchernev0Simona Kordeva1Ilia Batashki2Atanas Batashki3Heily Kirilova4Konstantin Stavrov5Onkoderma- Clinic for Dermatology, Venereology and Dermatologic SurgeryOnkoderma - Clinic for Dermatology, Venereology and Dermatologic Surgery Medical Institute of Ministry of InteriorMedical Institute of Ministry of InteriorMedical Institute of Ministry of InteriorDr Stavrov Aesthetics - Private clinic for dermatology , Venereology and Aesthetic medicine Erosive pustular dermatosis of the scalp (EPDS) is a rare condition which affects predominantly the adult population, and occurs on a previously photo-damaged bald scalp. The physical examination is presented with a large erythematous, erosive and crusted patches with granulation on an atrophic skin. The problem in patients with erosive pustular dermatosis of the scalp arises from the nonspecific clinical and histopathological findings, which can be misleading. Biopsy followed by careful histopathological verification is mandatory, although the finding is nonspecific.The histopathology findings are characterized by superficial erosions with mild neutrophil infiltrate, mainly intravascular and focally with neutrophil exocytosis. Focal parakeratosis, smoothed rete ridges without pronounced interface changes. Pronounced lymphoplasmacytic infiltrate with focal distribution in the dermis, giant cell reaction with the formation of a “foreign body” granuloma. We report a 58-year old male patient with a 1 year old lesion, suspected for skin cancer, later diagnosed with EPDS, which was successfully treated with topical clobetasol proprionate after 3-5 weeks. https://www.pagepress.org/journals/index.php/dr/article/view/9556erosive pustular dermatosis, topical treatment, neutrophil exocytosis, foreign body granuloma, clobetasol propionate |
| spellingShingle | Georgi Tchernev Simona Kordeva Ilia Batashki Atanas Batashki Heily Kirilova Konstantin Stavrov Erosive pustular dermatosis of the scalp: a pathogenetic мystery and therapeutic challenge Dermatology Reports erosive pustular dermatosis, topical treatment, neutrophil exocytosis, foreign body granuloma, clobetasol propionate |
| title | Erosive pustular dermatosis of the scalp: a pathogenetic мystery and therapeutic challenge |
| title_full | Erosive pustular dermatosis of the scalp: a pathogenetic мystery and therapeutic challenge |
| title_fullStr | Erosive pustular dermatosis of the scalp: a pathogenetic мystery and therapeutic challenge |
| title_full_unstemmed | Erosive pustular dermatosis of the scalp: a pathogenetic мystery and therapeutic challenge |
| title_short | Erosive pustular dermatosis of the scalp: a pathogenetic мystery and therapeutic challenge |
| title_sort | erosive pustular dermatosis of the scalp a pathogenetic мystery and therapeutic challenge |
| topic | erosive pustular dermatosis, topical treatment, neutrophil exocytosis, foreign body granuloma, clobetasol propionate |
| url | https://www.pagepress.org/journals/index.php/dr/article/view/9556 |
| work_keys_str_mv | AT georgitchernev erosivepustulardermatosisofthescalpapathogeneticmysteryandtherapeuticchallenge AT simonakordeva erosivepustulardermatosisofthescalpapathogeneticmysteryandtherapeuticchallenge AT iliabatashki erosivepustulardermatosisofthescalpapathogeneticmysteryandtherapeuticchallenge AT atanasbatashki erosivepustulardermatosisofthescalpapathogeneticmysteryandtherapeuticchallenge AT heilykirilova erosivepustulardermatosisofthescalpapathogeneticmysteryandtherapeuticchallenge AT konstantinstavrov erosivepustulardermatosisofthescalpapathogeneticmysteryandtherapeuticchallenge |