Prolonged exposure to acid and bile induces chromosome abnormalities that precede malignant transformation of benign Barrett’s epithelium

Prolonged exposure to acid and bile induces chromosome abnormalities that precede malignant transformation of benign Barrett’s epithelium

<p>Abstract</p> <p>Barrett’s esophagus (BE) is an asymptomatic, pre-malignant condition of the esophagus that can progress to esophageal adenocarcinoma (EAC). BE arises typically in individuals with long-standing gastroesophageal reflux disease (GERD). The neoplastic progression of...

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Bibliographic Details
Main Authors: Bajpai Manisha, Aviv Hana, Das Kiron M
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Molecular Cytogenetics
Subjects:
Barrett’s epithelium
BAR-T
Barrett’s epithelium carcinogenesis model
Aneuploidy
Polyploidy
Chromosomal aberrations
Genetic instability
Online Access:http://www.molecularcytogenetics.org/content/5/1/43

Internet

http://www.molecularcytogenetics.org/content/5/1/43

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