Osteosarcoma of the jaws: A retrospective study

Osteosarcoma is a primary malignant tumor of bone, which can involve jaws. This article reviews osteosarcoma of the jaws referred to the Department of oral pathology, dental faculty of Tehran University of Medical Sicences and Pathology Department of Cancer Institiute in Imam Khomeini Hospital durin...

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Main Authors: Baghaie F, Motahhary P
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2003-06-01
Series:Acta Medica Iranica
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/1052.pdf&manuscript_id=1052
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author Baghaie F
Motahhary P
author_facet Baghaie F
Motahhary P
author_sort Baghaie F
collection DOAJ
description Osteosarcoma is a primary malignant tumor of bone, which can involve jaws. This article reviews osteosarcoma of the jaws referred to the Department of oral pathology, dental faculty of Tehran University of Medical Sicences and Pathology Department of Cancer Institiute in Imam Khomeini Hospital during 30 years from 1349 to 1378 and also reviews jaw Osteosarcoma in English literature. The purpose of this review is comparing the clinical behaviour of jaw tumors with Osteosarcoma from elsewhere in the body and reporting the observations of clinical, histological and diagnostic findings. For this retrospective review the clinical, radiographic and histopathologic records of 42 patients were obtained, furthermore follow up results were also obtained from patients records. The mean age of patients was 35 years (range 9 to 61 years) with slight male predilection. The most common presenting features were swelling, pain and ulcer. Histologically, the lesions ranged from well-differentiated tumors with prominent osteoid formation to poorly differentiated tumors, which had bizarre cells and numerous mitosis especially atypical ones. Most of the lesions had areas of chondroid formation, but all of tumors showed neoplastic osteiod, of course in different degrees. The most important problem after treatment was local recurrence. Primary osteosarcomas of the jaws are a group of lesions, which are biologically distinct from long bones osteosarcoma and have better behaviour than them. More accurate determination of their clinical behaviour and their management will depend on complete follow up of patients and actual records of patients’ data.
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spelling doaj.art-61cf1245635f4d3a91a1bc31700820542022-12-22T00:51:49ZengTehran University of Medical SciencesActa Medica Iranica0044-60252003-06-01412113121Osteosarcoma of the jaws: A retrospective studyBaghaie FMotahhary POsteosarcoma is a primary malignant tumor of bone, which can involve jaws. This article reviews osteosarcoma of the jaws referred to the Department of oral pathology, dental faculty of Tehran University of Medical Sicences and Pathology Department of Cancer Institiute in Imam Khomeini Hospital during 30 years from 1349 to 1378 and also reviews jaw Osteosarcoma in English literature. The purpose of this review is comparing the clinical behaviour of jaw tumors with Osteosarcoma from elsewhere in the body and reporting the observations of clinical, histological and diagnostic findings. For this retrospective review the clinical, radiographic and histopathologic records of 42 patients were obtained, furthermore follow up results were also obtained from patients records. The mean age of patients was 35 years (range 9 to 61 years) with slight male predilection. The most common presenting features were swelling, pain and ulcer. Histologically, the lesions ranged from well-differentiated tumors with prominent osteoid formation to poorly differentiated tumors, which had bizarre cells and numerous mitosis especially atypical ones. Most of the lesions had areas of chondroid formation, but all of tumors showed neoplastic osteiod, of course in different degrees. The most important problem after treatment was local recurrence. Primary osteosarcomas of the jaws are a group of lesions, which are biologically distinct from long bones osteosarcoma and have better behaviour than them. More accurate determination of their clinical behaviour and their management will depend on complete follow up of patients and actual records of patients’ data.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/1052.pdf&manuscript_id=1052OsteosarcomaJawMalignant bone tumor
spellingShingle Baghaie F
Motahhary P
Osteosarcoma of the jaws: A retrospective study
Acta Medica Iranica
Osteosarcoma
Jaw
Malignant bone tumor
title Osteosarcoma of the jaws: A retrospective study
title_full Osteosarcoma of the jaws: A retrospective study
title_fullStr Osteosarcoma of the jaws: A retrospective study
title_full_unstemmed Osteosarcoma of the jaws: A retrospective study
title_short Osteosarcoma of the jaws: A retrospective study
title_sort osteosarcoma of the jaws a retrospective study
topic Osteosarcoma
Jaw
Malignant bone tumor
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/1052.pdf&manuscript_id=1052
work_keys_str_mv AT baghaief osteosarcomaofthejawsaretrospectivestudy
AT motahharyp osteosarcomaofthejawsaretrospectivestudy