Malignant Syndrome in Parkinson Disease Similar to Severe Infection

A 70-year-old woman with Parkinson disease was admitted to the emergency department with altered consciousness, fever and convulsive movements without experiencing withdrawal from antiparkinsonian medication. Six hours after the emergency department visit, the patient had a hyperpyrexia (> 40°C)...

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Main Authors: Dong Hun Lee, Jeong Mi Moon, Yong Soo Cho
Format: Article
Language:English
Published: Korean Society of Critical Care Medicine 2017-11-01
Series:Korean Journal of Critical Care Medicine
Subjects:
Online Access:http://www.kjccm.org/upload/pdf/kjccm-2016-00087.pdf
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author Dong Hun Lee
Jeong Mi Moon
Yong Soo Cho
author_facet Dong Hun Lee
Jeong Mi Moon
Yong Soo Cho
author_sort Dong Hun Lee
collection DOAJ
description A 70-year-old woman with Parkinson disease was admitted to the emergency department with altered consciousness, fever and convulsive movements without experiencing withdrawal from antiparkinsonian medication. Six hours after the emergency department visit, the patient had a hyperpyrexia (> 40°C) and a systolic blood pressure of 40 mmHg. There was no evidence of bacterial infection based on extensive workups. The patient was discharged without aggravation of Parkinson disease symptoms after treatment that included administration of dantrolene sodium, enforcement of continuous renal replacement therapy and cooling blankets. Malignant syndrome should be suspected if high fever occurs in Parkinson disease patients without evidence of a definitive infection.
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spelling doaj.art-61cf509b8da14c5a846cafe78d4997092022-12-22T01:22:40ZengKorean Society of Critical Care MedicineKorean Journal of Critical Care Medicine2383-48702383-48892017-11-0132435936210.4266/kjccm.2016.000871068Malignant Syndrome in Parkinson Disease Similar to Severe InfectionDong Hun LeeJeong Mi MoonYong Soo ChoA 70-year-old woman with Parkinson disease was admitted to the emergency department with altered consciousness, fever and convulsive movements without experiencing withdrawal from antiparkinsonian medication. Six hours after the emergency department visit, the patient had a hyperpyrexia (> 40°C) and a systolic blood pressure of 40 mmHg. There was no evidence of bacterial infection based on extensive workups. The patient was discharged without aggravation of Parkinson disease symptoms after treatment that included administration of dantrolene sodium, enforcement of continuous renal replacement therapy and cooling blankets. Malignant syndrome should be suspected if high fever occurs in Parkinson disease patients without evidence of a definitive infection.http://www.kjccm.org/upload/pdf/kjccm-2016-00087.pdfdehydrationfevermalignant syndromeparkinson disease
spellingShingle Dong Hun Lee
Jeong Mi Moon
Yong Soo Cho
Malignant Syndrome in Parkinson Disease Similar to Severe Infection
Korean Journal of Critical Care Medicine
dehydration
fever
malignant syndrome
parkinson disease
title Malignant Syndrome in Parkinson Disease Similar to Severe Infection
title_full Malignant Syndrome in Parkinson Disease Similar to Severe Infection
title_fullStr Malignant Syndrome in Parkinson Disease Similar to Severe Infection
title_full_unstemmed Malignant Syndrome in Parkinson Disease Similar to Severe Infection
title_short Malignant Syndrome in Parkinson Disease Similar to Severe Infection
title_sort malignant syndrome in parkinson disease similar to severe infection
topic dehydration
fever
malignant syndrome
parkinson disease
url http://www.kjccm.org/upload/pdf/kjccm-2016-00087.pdf
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