Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers
This letter is intended to clarify the clinical effectiveness of neuropeptide substance P (SP) in reducing age-related skin wrinkling. This is the first clinical study to evaluate the efficacy of the topical application of SP on wrinkle reduction. For the clinical study, we tested the efficacy of a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-05-01
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| Series: | Cosmetics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-9284/7/2/37 |
| _version_ | 1797567362142044160 |
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| author | Da Jung Kim Seul Bi Lee Song Sun Chang Jungsun Lee |
| author_facet | Da Jung Kim Seul Bi Lee Song Sun Chang Jungsun Lee |
| author_sort | Da Jung Kim |
| collection | DOAJ |
| description | This letter is intended to clarify the clinical effectiveness of neuropeptide substance P (SP) in reducing age-related skin wrinkling. This is the first clinical study to evaluate the efficacy of the topical application of SP on wrinkle reduction. For the clinical study, we tested the efficacy of a stable SP formulation known as SP-based hydrogel against skin aging in study participants. We found that this SP-based hydrogel reduced skin aging based on changes observed in several cutaneous parameters. |
| first_indexed | 2024-03-10T19:41:44Z |
| format | Article |
| id | doaj.art-61d1e5859c5a48858c5712e69759b3c0 |
| institution | Directory Open Access Journal |
| issn | 2079-9284 |
| language | English |
| last_indexed | 2024-03-10T19:41:44Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cosmetics |
| spelling | doaj.art-61d1e5859c5a48858c5712e69759b3c02023-11-20T01:13:10ZengMDPI AGCosmetics2079-92842020-05-01723710.3390/cosmetics7020037Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human VolunteersDa Jung Kim0Seul Bi Lee1Song Sun Chang2Jungsun Lee3Research and Development Institute, Biosolution, Seoul Technopark, 232 Gongneung-ro, Nowon-gu, Seoul 01811, KoreaResearch and Development Institute, Biosolution, Seoul Technopark, 232 Gongneung-ro, Nowon-gu, Seoul 01811, KoreaResearch and Development Institute, Biosolution, Seoul Technopark, 232 Gongneung-ro, Nowon-gu, Seoul 01811, KoreaResearch and Development Institute, Biosolution, Seoul Technopark, 232 Gongneung-ro, Nowon-gu, Seoul 01811, KoreaThis letter is intended to clarify the clinical effectiveness of neuropeptide substance P (SP) in reducing age-related skin wrinkling. This is the first clinical study to evaluate the efficacy of the topical application of SP on wrinkle reduction. For the clinical study, we tested the efficacy of a stable SP formulation known as SP-based hydrogel against skin aging in study participants. We found that this SP-based hydrogel reduced skin aging based on changes observed in several cutaneous parameters.https://www.mdpi.com/2079-9284/7/2/37substance Phydrogelanti-wrinkle efficacyclinical studycosmeceutical |
| spellingShingle | Da Jung Kim Seul Bi Lee Song Sun Chang Jungsun Lee Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers Cosmetics substance P hydrogel anti-wrinkle efficacy clinical study cosmeceutical |
| title | Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers |
| title_full | Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers |
| title_fullStr | Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers |
| title_full_unstemmed | Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers |
| title_short | Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers |
| title_sort | anti wrinkle efficacy of neuropeptide substance p based hydrogel in human volunteers |
| topic | substance P hydrogel anti-wrinkle efficacy clinical study cosmeceutical |
| url | https://www.mdpi.com/2079-9284/7/2/37 |
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