STATUS OF ACETYLCHOLINESTERASE MEDIATED ORGANOPHOSPHATE RESISTANCE IN CATTLE TICK, RHIPICEPHALUS MICROPLUS (ACARI: IXODIDAE)
Ticks, the haematophagus ectoparasites with worldwide distribution especially in tropical and sub-tropical regions, severely affect health and productivity of animals. Different classes of chemical acaricides like organochlorines, organophosphates, formamidines, synthetic pyrethroids and macrocycl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
West Bengal Veterinary Alumni Association
2024-04-01
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| Series: | Exploratory Animal and Medical Research |
| Subjects: | |
| Online Access: | https://animalmedicalresearch.org/Vol.14_Parasitology-Special-Issue_April_2024/STATUS%20OF%20ACETYLCHOLINESTERASE%20MEDIATED.pdf |
| Summary: | Ticks, the haematophagus ectoparasites with worldwide distribution especially in tropical
and sub-tropical regions, severely affect health and productivity of animals. Different classes of chemical
acaricides like organochlorines, organophosphates, formamidines, synthetic pyrethroids and macrocyclic
lactones are currently used for controlling the tick infestations. The continuous and indiscriminate
treatments often leads to acaricide resistance, environmental pollution and residues in meat and milk
products. Organophosphate (OP) compounds were initially introduced as a replacement to organochlorines
as they were non-persistent and did not accumulate in the fat tissues. The global scenario of OP resistance
development in cattle tick, Rhipicephalus microplus has been summarized in the present review. The
various resistance mechanisms against OPs in R. microplus include target site modification in the
acetylcholinesterase (AChE), and carboxylesterase (CE) gene, as well as metabolic detoxification. |
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| ISSN: | 2277-470X 2319-247X |