HASTE MRI sequence findings correlate with loss of deep pain perception in dogs with thoracolumbar disc extrusion
Abstract Background Thoracolumbar intervertebral disc extrusion (TL IVDE) is a common reason for the veterinary hospital admission. Various imaging factors including degree and length of compression have been tested for correlation with clinical severity, but no reliable correlation has been found....
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| Format: | Article |
| Language: | English |
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Wiley
2023-03-01
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| Series: | Veterinary Medicine and Science |
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| Online Access: | https://doi.org/10.1002/vms3.974 |
| _version_ | 1797866296528863232 |
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| author | Sam Khan Paul Freeman |
| author_facet | Sam Khan Paul Freeman |
| author_sort | Sam Khan |
| collection | DOAJ |
| description | Abstract Background Thoracolumbar intervertebral disc extrusion (TL IVDE) is a common reason for the veterinary hospital admission. Various imaging factors including degree and length of compression have been tested for correlation with clinical severity, but no reliable correlation has been found. Half‐Fourier acquisition single‐shot turbo spin echo (HASTE) magnetic resonance imaging (MRI) sequences highlight the dorsal and ventral cerebrospinal fluid (CSF) columns and have been used to demonstrate spinal cord swelling in dogs with TL IVDE. This has been used as a predictor of progressive ascending‐descending myelomalacia but has not been correlated with neurological grade. Objective This study aims to investigate the correlation between the attenuation of CSF HASTE signal and clinical severity in dogs suffering from TL disc extrusions. Methods Dogs less than 15 kg who were non‐ambulatory due to suspected TL IVDE were prospectively recruited for a study into conservative management. MRI studies were undertaken under sedation including HASTE sequences. The ratio of the length of CSF attenuation to the length of the L2 vertebra was calculated and correlated with clinical severity. Results Twenty dogs met the inclusion criteria. No statistically significant difference was demonstrated between the mean CSF attenuation and neurological grade (p = 0.17 but there was a significant difference in the mean CSF attenuation in those who retained deep pain perception and those who did not (p = 0.02). Time to loss of ambulation was also found to not be correlated with CSF attenuation (p = 0.95). Conclusion In conclusion, the length of CSF attenuation of HASTE MRI sequences in dogs less than 15 kg suffering from IVDEs may be correlated with a loss of deep pain perception. |
| first_indexed | 2024-04-09T23:21:42Z |
| format | Article |
| id | doaj.art-61d7b826b35041dc9adc93d4fa834ec8 |
| institution | Directory Open Access Journal |
| issn | 2053-1095 |
| language | English |
| last_indexed | 2024-04-09T23:21:42Z |
| publishDate | 2023-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine and Science |
| spelling | doaj.art-61d7b826b35041dc9adc93d4fa834ec82023-03-21T15:53:53ZengWileyVeterinary Medicine and Science2053-10952023-03-019260460810.1002/vms3.974HASTE MRI sequence findings correlate with loss of deep pain perception in dogs with thoracolumbar disc extrusionSam Khan0Paul Freeman1Queen's Veterinary School Hospital Cambridge UKQueen's Veterinary School Hospital Cambridge UKAbstract Background Thoracolumbar intervertebral disc extrusion (TL IVDE) is a common reason for the veterinary hospital admission. Various imaging factors including degree and length of compression have been tested for correlation with clinical severity, but no reliable correlation has been found. Half‐Fourier acquisition single‐shot turbo spin echo (HASTE) magnetic resonance imaging (MRI) sequences highlight the dorsal and ventral cerebrospinal fluid (CSF) columns and have been used to demonstrate spinal cord swelling in dogs with TL IVDE. This has been used as a predictor of progressive ascending‐descending myelomalacia but has not been correlated with neurological grade. Objective This study aims to investigate the correlation between the attenuation of CSF HASTE signal and clinical severity in dogs suffering from TL disc extrusions. Methods Dogs less than 15 kg who were non‐ambulatory due to suspected TL IVDE were prospectively recruited for a study into conservative management. MRI studies were undertaken under sedation including HASTE sequences. The ratio of the length of CSF attenuation to the length of the L2 vertebra was calculated and correlated with clinical severity. Results Twenty dogs met the inclusion criteria. No statistically significant difference was demonstrated between the mean CSF attenuation and neurological grade (p = 0.17 but there was a significant difference in the mean CSF attenuation in those who retained deep pain perception and those who did not (p = 0.02). Time to loss of ambulation was also found to not be correlated with CSF attenuation (p = 0.95). Conclusion In conclusion, the length of CSF attenuation of HASTE MRI sequences in dogs less than 15 kg suffering from IVDEs may be correlated with a loss of deep pain perception.https://doi.org/10.1002/vms3.974intervertebral disc extrusionMRIspine |
| spellingShingle | Sam Khan Paul Freeman HASTE MRI sequence findings correlate with loss of deep pain perception in dogs with thoracolumbar disc extrusion Veterinary Medicine and Science intervertebral disc extrusion MRI spine |
| title | HASTE MRI sequence findings correlate with loss of deep pain perception in dogs with thoracolumbar disc extrusion |
| title_full | HASTE MRI sequence findings correlate with loss of deep pain perception in dogs with thoracolumbar disc extrusion |
| title_fullStr | HASTE MRI sequence findings correlate with loss of deep pain perception in dogs with thoracolumbar disc extrusion |
| title_full_unstemmed | HASTE MRI sequence findings correlate with loss of deep pain perception in dogs with thoracolumbar disc extrusion |
| title_short | HASTE MRI sequence findings correlate with loss of deep pain perception in dogs with thoracolumbar disc extrusion |
| title_sort | haste mri sequence findings correlate with loss of deep pain perception in dogs with thoracolumbar disc extrusion |
| topic | intervertebral disc extrusion MRI spine |
| url | https://doi.org/10.1002/vms3.974 |
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