Personalized medicine: A step forward in dental treatment

The study of variations of DNA and RNA characteristics as related to drug response is known as pharmacogenomics. The application of pharmacogenomics to the clinical management of an individual is referred to as "personalized medicine." Personalized medicine aims to individualize care based...

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Main Authors: Surbhi, Anand Kumar, Archna Nagpal, Puneeta Vohra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Indian Academy of Oral Medicine and Radiology
Subjects:
Online Access:http://www.jiaomr.in/article.asp?issn=0972-1363;year=2015;volume=27;issue=1;spage=76;epage=80;aulast=Kumar
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author Surbhi
Anand Kumar
Archna Nagpal
Puneeta Vohra
author_facet Surbhi
Anand Kumar
Archna Nagpal
Puneeta Vohra
author_sort Surbhi
collection DOAJ
description The study of variations of DNA and RNA characteristics as related to drug response is known as pharmacogenomics. The application of pharmacogenomics to the clinical management of an individual is referred to as "personalized medicine." Personalized medicine aims to individualize care based on a person′s unique genetic profile by using advanced molecular tools like DNA profiling, gene mapping, receptor gene amplification test, fluorescence in situ hybridization (FISH), microarray test, Hercep Test, AmpliChip CYP450 Test, etc. This is relatively a new field that combines genomics (the study of genes and their functions) and pharmacology (the science of drugs) to develop effective, safe medications and doses that will be tailored to a person′s genetic makeup. Now personalized medicine has a wide range of applications such as management of cancer, cardiovascular disorders, depression, bipolar disorders, attention deficit disorders, HIV, tuberculosis, asthma, diabetes, and also in the management of pain. This is the first article focusing on its mechanism, overview of the developments, benefits, challenges, and its applications, particularly in dentistry.
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spelling doaj.art-61da6ad12041433aa0e0eb6f2b8dba532022-12-22T00:14:14ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13630975-15722015-01-01271768010.4103/0972-1363.167089Personalized medicine: A step forward in dental treatmentSurbhiAnand KumarArchna NagpalPuneeta VohraThe study of variations of DNA and RNA characteristics as related to drug response is known as pharmacogenomics. The application of pharmacogenomics to the clinical management of an individual is referred to as "personalized medicine." Personalized medicine aims to individualize care based on a person′s unique genetic profile by using advanced molecular tools like DNA profiling, gene mapping, receptor gene amplification test, fluorescence in situ hybridization (FISH), microarray test, Hercep Test, AmpliChip CYP450 Test, etc. This is relatively a new field that combines genomics (the study of genes and their functions) and pharmacology (the science of drugs) to develop effective, safe medications and doses that will be tailored to a person′s genetic makeup. Now personalized medicine has a wide range of applications such as management of cancer, cardiovascular disorders, depression, bipolar disorders, attention deficit disorders, HIV, tuberculosis, asthma, diabetes, and also in the management of pain. This is the first article focusing on its mechanism, overview of the developments, benefits, challenges, and its applications, particularly in dentistry.http://www.jiaomr.in/article.asp?issn=0972-1363;year=2015;volume=27;issue=1;spage=76;epage=80;aulast=KumarGenetic mappingpersonalized medicinepharmacogeneticspharmacogenomics
spellingShingle Surbhi
Anand Kumar
Archna Nagpal
Puneeta Vohra
Personalized medicine: A step forward in dental treatment
Journal of Indian Academy of Oral Medicine and Radiology
Genetic mapping
personalized medicine
pharmacogenetics
pharmacogenomics
title Personalized medicine: A step forward in dental treatment
title_full Personalized medicine: A step forward in dental treatment
title_fullStr Personalized medicine: A step forward in dental treatment
title_full_unstemmed Personalized medicine: A step forward in dental treatment
title_short Personalized medicine: A step forward in dental treatment
title_sort personalized medicine a step forward in dental treatment
topic Genetic mapping
personalized medicine
pharmacogenetics
pharmacogenomics
url http://www.jiaomr.in/article.asp?issn=0972-1363;year=2015;volume=27;issue=1;spage=76;epage=80;aulast=Kumar
work_keys_str_mv AT surbhi personalizedmedicineastepforwardindentaltreatment
AT anandkumar personalizedmedicineastepforwardindentaltreatment
AT archnanagpal personalizedmedicineastepforwardindentaltreatment
AT puneetavohra personalizedmedicineastepforwardindentaltreatment