Uterine Arteries Embolization—A Rescue Tool for Acute Vaginal Bleeding in Late Stages of Gynecologic Malignancies
Background: Uterine arteries embolization (UAE) is a minimally invasive procedure with good results when it is used as interventional treatment for patients diagnosed with benign or malignant uterine tumors. The main gynecological malignancies that are complicated by hemorrhages and would benefit fr...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IMR Press
2022-06-01
|
| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/49/6/10.31083/j.ceog4906142 |
| _version_ | 1811237747614023680 |
|---|---|
| author | Roxana Elena Bohîlțea Bogdan Dorobaț Maria Mădalina Doldur Ana-Maria Cioca Ionița Ducu Bianca Margareta Mihai Corina-Aurelia Zugravu Corina Grigoriu Valentin Varlas |
| author_facet | Roxana Elena Bohîlțea Bogdan Dorobaț Maria Mădalina Doldur Ana-Maria Cioca Ionița Ducu Bianca Margareta Mihai Corina-Aurelia Zugravu Corina Grigoriu Valentin Varlas |
| author_sort | Roxana Elena Bohîlțea |
| collection | DOAJ |
| description | Background: Uterine arteries embolization (UAE) is a minimally invasive procedure with good results when it is used as interventional treatment for patients diagnosed with benign or malignant uterine tumors. The main gynecological malignancies that are complicated by hemorrhages and would benefit from UAE are cervical cancer and endometrial cancer in late inoperable stages or following surgery. Methods: During five years, in the Bucharest University Emergency Hospital’s Obstetrics and Gynecology Department, from 605 patients to whom trans-catheter embolization of the uterine arteries was performed, 33 (5.45%) were diagnosed with cervical cancer (n = 31) and endometrial cancer (n = 2) in the advanced stage addressed for heavy acute vaginal bleeding and secondary anemia. Results: For those patients, UAE was used as palliative treatment. The average age of the patients in the evaluated group was 48.7 ± 8.3 years, and the average number of days of hospitalization was 4.72 ± 2.97 (range 1–11). The benefits of UAE include cessation of bleeding in up to 100% of cases and expanding the window of opportunity for secondary anemia correction. The most common side effects (pain, nausea) could be managed with mild analgesics and easily-accessible antiemetics. Conclusions: Considering these patients’ fragile advanced oncological status, surgical ligation should be adopted only in centers where UAE is not available. The article strengthens the need for interventional radiology departments in all regional emergency centers. |
| first_indexed | 2024-04-12T12:28:38Z |
| format | Article |
| id | doaj.art-61db4647cea64856b6b1062097dc12fa |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-04-12T12:28:38Z |
| publishDate | 2022-06-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-61db4647cea64856b6b1062097dc12fa2022-12-22T03:33:05ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632022-06-0149614210.31083/j.ceog4906142S0390-6663(22)01821-8Uterine Arteries Embolization—A Rescue Tool for Acute Vaginal Bleeding in Late Stages of Gynecologic MalignanciesRoxana Elena Bohîlțea0Bogdan Dorobaț1Maria Mădalina Doldur2Ana-Maria Cioca3Ionița Ducu4Bianca Margareta Mihai5Corina-Aurelia Zugravu6Corina Grigoriu7Valentin Varlas8Department of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of Interventional Radiology, Bucharest University Emergency Hospital, 050098 Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, 020021 Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, 020021 Bucharest, RomaniaDepartment of Obstetrics and Gynecology, Life Memorial Hospital, 010719 Bucharest, RomaniaDepartment of Obstetrics and Gynecology, Filantropia Clinical Hospital, 011171 Bucharest, RomaniaDepartment of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, RomaniaBackground: Uterine arteries embolization (UAE) is a minimally invasive procedure with good results when it is used as interventional treatment for patients diagnosed with benign or malignant uterine tumors. The main gynecological malignancies that are complicated by hemorrhages and would benefit from UAE are cervical cancer and endometrial cancer in late inoperable stages or following surgery. Methods: During five years, in the Bucharest University Emergency Hospital’s Obstetrics and Gynecology Department, from 605 patients to whom trans-catheter embolization of the uterine arteries was performed, 33 (5.45%) were diagnosed with cervical cancer (n = 31) and endometrial cancer (n = 2) in the advanced stage addressed for heavy acute vaginal bleeding and secondary anemia. Results: For those patients, UAE was used as palliative treatment. The average age of the patients in the evaluated group was 48.7 ± 8.3 years, and the average number of days of hospitalization was 4.72 ± 2.97 (range 1–11). The benefits of UAE include cessation of bleeding in up to 100% of cases and expanding the window of opportunity for secondary anemia correction. The most common side effects (pain, nausea) could be managed with mild analgesics and easily-accessible antiemetics. Conclusions: Considering these patients’ fragile advanced oncological status, surgical ligation should be adopted only in centers where UAE is not available. The article strengthens the need for interventional radiology departments in all regional emergency centers.https://www.imrpress.com/journal/CEOG/49/6/10.31083/j.ceog4906142uterine artery embolizationcervical cancerendometrial canceracute uterine bleedingpalliationheavy vaginal bleedingsecondary anemiamesh |
| spellingShingle | Roxana Elena Bohîlțea Bogdan Dorobaț Maria Mădalina Doldur Ana-Maria Cioca Ionița Ducu Bianca Margareta Mihai Corina-Aurelia Zugravu Corina Grigoriu Valentin Varlas Uterine Arteries Embolization—A Rescue Tool for Acute Vaginal Bleeding in Late Stages of Gynecologic Malignancies Clinical and Experimental Obstetrics & Gynecology uterine artery embolization cervical cancer endometrial cancer acute uterine bleeding palliation heavy vaginal bleeding secondary anemia mesh |
| title | Uterine Arteries Embolization—A Rescue Tool for Acute Vaginal Bleeding in Late Stages of Gynecologic Malignancies |
| title_full | Uterine Arteries Embolization—A Rescue Tool for Acute Vaginal Bleeding in Late Stages of Gynecologic Malignancies |
| title_fullStr | Uterine Arteries Embolization—A Rescue Tool for Acute Vaginal Bleeding in Late Stages of Gynecologic Malignancies |
| title_full_unstemmed | Uterine Arteries Embolization—A Rescue Tool for Acute Vaginal Bleeding in Late Stages of Gynecologic Malignancies |
| title_short | Uterine Arteries Embolization—A Rescue Tool for Acute Vaginal Bleeding in Late Stages of Gynecologic Malignancies |
| title_sort | uterine arteries embolization a rescue tool for acute vaginal bleeding in late stages of gynecologic malignancies |
| topic | uterine artery embolization cervical cancer endometrial cancer acute uterine bleeding palliation heavy vaginal bleeding secondary anemia mesh |
| url | https://www.imrpress.com/journal/CEOG/49/6/10.31083/j.ceog4906142 |
| work_keys_str_mv | AT roxanaelenabohiltea uterinearteriesembolizationarescuetoolforacutevaginalbleedinginlatestagesofgynecologicmalignancies AT bogdandorobat uterinearteriesembolizationarescuetoolforacutevaginalbleedinginlatestagesofgynecologicmalignancies AT mariamadalinadoldur uterinearteriesembolizationarescuetoolforacutevaginalbleedinginlatestagesofgynecologicmalignancies AT anamariacioca uterinearteriesembolizationarescuetoolforacutevaginalbleedinginlatestagesofgynecologicmalignancies AT ionitaducu uterinearteriesembolizationarescuetoolforacutevaginalbleedinginlatestagesofgynecologicmalignancies AT biancamargaretamihai uterinearteriesembolizationarescuetoolforacutevaginalbleedinginlatestagesofgynecologicmalignancies AT corinaaureliazugravu uterinearteriesembolizationarescuetoolforacutevaginalbleedinginlatestagesofgynecologicmalignancies AT corinagrigoriu uterinearteriesembolizationarescuetoolforacutevaginalbleedinginlatestagesofgynecologicmalignancies AT valentinvarlas uterinearteriesembolizationarescuetoolforacutevaginalbleedinginlatestagesofgynecologicmalignancies |