Association of interarm systolic blood pressure difference with atherosclerosis and left ventricular hypertrophy.

An interarm systolic blood pressure (SBP) difference of 10 mmHg or more have been associated with peripheral artery disease and adverse cardiovascular outcomes. We investigated whether an association exists between this difference and ankle-brachial index (ABI), brachial-ankle pulse wave velocity (b...

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Main Authors: Ho-Ming Su, Tsung-Hsien Lin, Po-Chao Hsu, Chun-Yuan Chu, Wen-Hsien Lee, Szu-Chia Chen, Chee-Siong Lee, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3426512?pdf=render
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author Ho-Ming Su
Tsung-Hsien Lin
Po-Chao Hsu
Chun-Yuan Chu
Wen-Hsien Lee
Szu-Chia Chen
Chee-Siong Lee
Wen-Chol Voon
Wen-Ter Lai
Sheng-Hsiung Sheu
author_facet Ho-Ming Su
Tsung-Hsien Lin
Po-Chao Hsu
Chun-Yuan Chu
Wen-Hsien Lee
Szu-Chia Chen
Chee-Siong Lee
Wen-Chol Voon
Wen-Ter Lai
Sheng-Hsiung Sheu
author_sort Ho-Ming Su
collection DOAJ
description An interarm systolic blood pressure (SBP) difference of 10 mmHg or more have been associated with peripheral artery disease and adverse cardiovascular outcomes. We investigated whether an association exists between this difference and ankle-brachial index (ABI), brachial-ankle pulse wave velocity (baPWV), and echocardiographic parameters. A total of 1120 patients were included in the study. The bilateral arm blood pressures were measured simultaneously by an ABI-form device. The values of ABI and baPWV were also obtained from the same device. Clinical data, ABI<0.9, baPWV, echocariographic parameters, and an interarm SBP difference ≥10 mmHg were compared and analyzed. We performed two multivariate forward analyses for determining the factors associated with an interarm SBP difference ≥10 mmHg [model 1: significant variables in univariate analysis except left ventricular mass index (LVMI); model 2: significant variables in univariate analysis except ABI<0.9 and baPWV]. The ABI<0.9 and high baPWV in model 1 and high LVMI in model 2 were independently associated with an interarm SBP difference ≥10 mmHg. Female, hypertension, and high body mass index were also associated with an interarm SBP difference ≥10 mmHg. Our study demonstrated that ABI<0.9, high baPWV, and high LVMI were independently associated with an interarm SBP difference of 10 mmHg or more. Detection of an interarm SBP difference may provide a simple method of detecting patients at increased risk of atherosclerosis and left ventricular hypertrophy.
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spelling doaj.art-61db53cc4e014f9a8acc966e055683a22022-12-21T19:43:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0178e4117310.1371/journal.pone.0041173Association of interarm systolic blood pressure difference with atherosclerosis and left ventricular hypertrophy.Ho-Ming SuTsung-Hsien LinPo-Chao HsuChun-Yuan ChuWen-Hsien LeeSzu-Chia ChenChee-Siong LeeWen-Chol VoonWen-Ter LaiSheng-Hsiung SheuAn interarm systolic blood pressure (SBP) difference of 10 mmHg or more have been associated with peripheral artery disease and adverse cardiovascular outcomes. We investigated whether an association exists between this difference and ankle-brachial index (ABI), brachial-ankle pulse wave velocity (baPWV), and echocardiographic parameters. A total of 1120 patients were included in the study. The bilateral arm blood pressures were measured simultaneously by an ABI-form device. The values of ABI and baPWV were also obtained from the same device. Clinical data, ABI<0.9, baPWV, echocariographic parameters, and an interarm SBP difference ≥10 mmHg were compared and analyzed. We performed two multivariate forward analyses for determining the factors associated with an interarm SBP difference ≥10 mmHg [model 1: significant variables in univariate analysis except left ventricular mass index (LVMI); model 2: significant variables in univariate analysis except ABI<0.9 and baPWV]. The ABI<0.9 and high baPWV in model 1 and high LVMI in model 2 were independently associated with an interarm SBP difference ≥10 mmHg. Female, hypertension, and high body mass index were also associated with an interarm SBP difference ≥10 mmHg. Our study demonstrated that ABI<0.9, high baPWV, and high LVMI were independently associated with an interarm SBP difference of 10 mmHg or more. Detection of an interarm SBP difference may provide a simple method of detecting patients at increased risk of atherosclerosis and left ventricular hypertrophy.http://europepmc.org/articles/PMC3426512?pdf=render
spellingShingle Ho-Ming Su
Tsung-Hsien Lin
Po-Chao Hsu
Chun-Yuan Chu
Wen-Hsien Lee
Szu-Chia Chen
Chee-Siong Lee
Wen-Chol Voon
Wen-Ter Lai
Sheng-Hsiung Sheu
Association of interarm systolic blood pressure difference with atherosclerosis and left ventricular hypertrophy.
PLoS ONE
title Association of interarm systolic blood pressure difference with atherosclerosis and left ventricular hypertrophy.
title_full Association of interarm systolic blood pressure difference with atherosclerosis and left ventricular hypertrophy.
title_fullStr Association of interarm systolic blood pressure difference with atherosclerosis and left ventricular hypertrophy.
title_full_unstemmed Association of interarm systolic blood pressure difference with atherosclerosis and left ventricular hypertrophy.
title_short Association of interarm systolic blood pressure difference with atherosclerosis and left ventricular hypertrophy.
title_sort association of interarm systolic blood pressure difference with atherosclerosis and left ventricular hypertrophy
url http://europepmc.org/articles/PMC3426512?pdf=render
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