Positive correlation between snoring and dyslipidemia in adults: results from NHANES
Abstract Background A few studies have shown that snoring, in certain populations, is associated with dyslipidemia. However, there are currently no large-scale national studies available that explore this association. Thus, for further clarification, studies using a large sample of the general popul...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | Lipids in Health and Disease |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12944-023-01839-7 |
| _version_ | 1827922765275987968 |
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| author | Ying Tian Dongna Li Huijuan Mu Sining Wei Dong Guo |
| author_facet | Ying Tian Dongna Li Huijuan Mu Sining Wei Dong Guo |
| author_sort | Ying Tian |
| collection | DOAJ |
| description | Abstract Background A few studies have shown that snoring, in certain populations, is associated with dyslipidemia. However, there are currently no large-scale national studies available that explore this association. Thus, for further clarification, studies using a large sample of the general population need to be conducted. This study aimed to explore this association using the National Health and Nutrition Examination Survey (NHANES) database. Methods A cross-sectional survey was conducted using data from the NHANES database; 2005 to 2008 and 2015 to 2018 datasets were used (weighted to be representative of United States adults aged ≥ 20 years). Information on snoring status, lipid levels, and confounding factors were included. Logistic regression of the generalized linear model was used to analyze the relationship between snoring and dyslipidemia, and hierarchical analysis, interaction analysis, and sensitivity analysis were used to explore the stability of the results. Results Data from 28,687 participants were analyzed, and 67% of the participants had some degree of snoring. The fully adjusted multivariate logistic regression results demonstrated that snoring frequency was significantly positively associated with dyslipidemia (P < 0.001 for linear trend). Adjusted odds ratios (aORs) of dyslipidemia among those who snored rarely, occasionally, and frequently were 1.1 (95% confidence interval [CI], 1.02–1.18), 1.23 (95% CI, 1.10–1.38), and 1.43 (95% CI, 1.29–1.58), respectively, compared with that among those who never snored. In addition, age and snoring frequency showed a correlation (P = 0.02). Sensitivity analysis demonstrated that frequent snoring was significantly associated with lipid levels (all P ≤ 0.01 for linear trend), including increased low-density lipoprotein cholesterol (LDL-C) (β = 0.09 mmol/L; 95% CI, 0.02–0.16), triglyceride (TG) (β = 0.18 mmol/L; 95% CI, 0.10–0.26), total cholesterol (TC) (β = 0.11 mmol/L; 95% CI, 0.05–0.16), and decreased high-density lipoprotein cholesterol (HDL-C) (β=-0.04 mmol/L; 95% CI, -0.06–-0.03). Conclusions A statistically significant positive association was identified between sleep snoring and dyslipidemia. It was suggested that sleep snoring interventions may reduce the risk of dyslipidemia. |
| first_indexed | 2024-03-13T04:47:26Z |
| format | Article |
| id | doaj.art-61de752fada54560a3bc28c7ed833c8a |
| institution | Directory Open Access Journal |
| issn | 1476-511X |
| language | English |
| last_indexed | 2024-03-13T04:47:26Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Lipids in Health and Disease |
| spelling | doaj.art-61de752fada54560a3bc28c7ed833c8a2023-06-18T11:23:46ZengBMCLipids in Health and Disease1476-511X2023-06-0122111210.1186/s12944-023-01839-7Positive correlation between snoring and dyslipidemia in adults: results from NHANESYing Tian0Dongna Li1Huijuan Mu2Sining Wei3Dong Guo4Clinical Research Center, Affiliated Hospital of Shandong, University of Traditional Chinese MedicineDepartment of Cardiology, Affiliated Hospital of Shandong University of Traditional Chinese MedicineDrug clinical trial facility, Affiliated Hospital of Shandong University of Traditional Chinese MedicinePrevention and treatment center, Affiliated Hospital of Shandong University of Traditional Chinese MedicineBasic Medical School, College of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineAbstract Background A few studies have shown that snoring, in certain populations, is associated with dyslipidemia. However, there are currently no large-scale national studies available that explore this association. Thus, for further clarification, studies using a large sample of the general population need to be conducted. This study aimed to explore this association using the National Health and Nutrition Examination Survey (NHANES) database. Methods A cross-sectional survey was conducted using data from the NHANES database; 2005 to 2008 and 2015 to 2018 datasets were used (weighted to be representative of United States adults aged ≥ 20 years). Information on snoring status, lipid levels, and confounding factors were included. Logistic regression of the generalized linear model was used to analyze the relationship between snoring and dyslipidemia, and hierarchical analysis, interaction analysis, and sensitivity analysis were used to explore the stability of the results. Results Data from 28,687 participants were analyzed, and 67% of the participants had some degree of snoring. The fully adjusted multivariate logistic regression results demonstrated that snoring frequency was significantly positively associated with dyslipidemia (P < 0.001 for linear trend). Adjusted odds ratios (aORs) of dyslipidemia among those who snored rarely, occasionally, and frequently were 1.1 (95% confidence interval [CI], 1.02–1.18), 1.23 (95% CI, 1.10–1.38), and 1.43 (95% CI, 1.29–1.58), respectively, compared with that among those who never snored. In addition, age and snoring frequency showed a correlation (P = 0.02). Sensitivity analysis demonstrated that frequent snoring was significantly associated with lipid levels (all P ≤ 0.01 for linear trend), including increased low-density lipoprotein cholesterol (LDL-C) (β = 0.09 mmol/L; 95% CI, 0.02–0.16), triglyceride (TG) (β = 0.18 mmol/L; 95% CI, 0.10–0.26), total cholesterol (TC) (β = 0.11 mmol/L; 95% CI, 0.05–0.16), and decreased high-density lipoprotein cholesterol (HDL-C) (β=-0.04 mmol/L; 95% CI, -0.06–-0.03). Conclusions A statistically significant positive association was identified between sleep snoring and dyslipidemia. It was suggested that sleep snoring interventions may reduce the risk of dyslipidemia.https://doi.org/10.1186/s12944-023-01839-7SnoringDyslipidemiaCross-sectional study |
| spellingShingle | Ying Tian Dongna Li Huijuan Mu Sining Wei Dong Guo Positive correlation between snoring and dyslipidemia in adults: results from NHANES Lipids in Health and Disease Snoring Dyslipidemia Cross-sectional study |
| title | Positive correlation between snoring and dyslipidemia in adults: results from NHANES |
| title_full | Positive correlation between snoring and dyslipidemia in adults: results from NHANES |
| title_fullStr | Positive correlation between snoring and dyslipidemia in adults: results from NHANES |
| title_full_unstemmed | Positive correlation between snoring and dyslipidemia in adults: results from NHANES |
| title_short | Positive correlation between snoring and dyslipidemia in adults: results from NHANES |
| title_sort | positive correlation between snoring and dyslipidemia in adults results from nhanes |
| topic | Snoring Dyslipidemia Cross-sectional study |
| url | https://doi.org/10.1186/s12944-023-01839-7 |
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