Research Progress of Protein-Based Bioactive Substance Nanoparticles
Bioactive substances exhibit various physiological activities—such as antimicrobial, antioxidant, and anticancer activities—and have great potential for application in food, pharmaceuticals, and nutraceuticals. However, the low solubility, chemical instability, and low bioavailability of bioactive s...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Foods |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2304-8158/12/16/2999 |
| _version_ | 1797584757793488896 |
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| author | Mengqing Han Kunlun Liu Xin Liu Muhammad Tayyab Rashid Huiyan Zhang Meiyue Wang |
| author_facet | Mengqing Han Kunlun Liu Xin Liu Muhammad Tayyab Rashid Huiyan Zhang Meiyue Wang |
| author_sort | Mengqing Han |
| collection | DOAJ |
| description | Bioactive substances exhibit various physiological activities—such as antimicrobial, antioxidant, and anticancer activities—and have great potential for application in food, pharmaceuticals, and nutraceuticals. However, the low solubility, chemical instability, and low bioavailability of bioactive substances limit their application in the food industry. Using nanotechnology to prepare protein nanoparticles to encapsulate and deliver active substances is a promising approach due to the abundance, biocompatibility, and biodegradability of proteins. Common protein-based nanocarriers include nano-emulsions, nano-gels, nanoparticles, and nano complexes. In this review, we give an overview of protein-based nanoparticle fabrication methods, highlighting their pros and cons. Additionally, we discuss the applications and current issues regarding the utilization of protein-based nanoparticles in the food industry. Finally, we provide perspectives on future development directions, with a focus on classifying bioactive substances and their functional properties. |
| first_indexed | 2024-03-10T23:57:15Z |
| format | Article |
| id | doaj.art-61dfa4237e794f5fad877314b89824a8 |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-10T23:57:15Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-61dfa4237e794f5fad877314b89824a82023-11-19T01:05:11ZengMDPI AGFoods2304-81582023-08-011216299910.3390/foods12162999Research Progress of Protein-Based Bioactive Substance NanoparticlesMengqing Han0Kunlun Liu1Xin Liu2Muhammad Tayyab Rashid3Huiyan Zhang4Meiyue Wang5College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, ChinaZhengzhou Ruipu Biological Engineering Co., Ltd., Zhengzhou 450001, ChinaCollege of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, ChinaBioactive substances exhibit various physiological activities—such as antimicrobial, antioxidant, and anticancer activities—and have great potential for application in food, pharmaceuticals, and nutraceuticals. However, the low solubility, chemical instability, and low bioavailability of bioactive substances limit their application in the food industry. Using nanotechnology to prepare protein nanoparticles to encapsulate and deliver active substances is a promising approach due to the abundance, biocompatibility, and biodegradability of proteins. Common protein-based nanocarriers include nano-emulsions, nano-gels, nanoparticles, and nano complexes. In this review, we give an overview of protein-based nanoparticle fabrication methods, highlighting their pros and cons. Additionally, we discuss the applications and current issues regarding the utilization of protein-based nanoparticles in the food industry. Finally, we provide perspectives on future development directions, with a focus on classifying bioactive substances and their functional properties.https://www.mdpi.com/2304-8158/12/16/2999bioactive substancesproteinsnanoparticlesencapsulationpreparation method |
| spellingShingle | Mengqing Han Kunlun Liu Xin Liu Muhammad Tayyab Rashid Huiyan Zhang Meiyue Wang Research Progress of Protein-Based Bioactive Substance Nanoparticles Foods bioactive substances proteins nanoparticles encapsulation preparation method |
| title | Research Progress of Protein-Based Bioactive Substance Nanoparticles |
| title_full | Research Progress of Protein-Based Bioactive Substance Nanoparticles |
| title_fullStr | Research Progress of Protein-Based Bioactive Substance Nanoparticles |
| title_full_unstemmed | Research Progress of Protein-Based Bioactive Substance Nanoparticles |
| title_short | Research Progress of Protein-Based Bioactive Substance Nanoparticles |
| title_sort | research progress of protein based bioactive substance nanoparticles |
| topic | bioactive substances proteins nanoparticles encapsulation preparation method |
| url | https://www.mdpi.com/2304-8158/12/16/2999 |
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