Virus–Host Interaction Gets <i>Curiouser and Curiouser</i>. PART I: Phage P1<i>vir</i> Enhanced Development in an <i>E. coli</i> DksA-Deficient Cell

Virus–Host Interaction Gets <i>Curiouser and Curiouser</i>. PART I: Phage P1<i>vir</i> Enhanced Development in an <i>E. coli</i> DksA-Deficient Cell

Bacteriophage P1 is among the best described bacterial viruses used in molecular biology. Here, we report that deficiency in the host cell DksA protein, an <i>E. coli</i> global transcription regulator, improves P1 lytic development. Using genetic and microbiological approaches, we inves...

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Bibliographic Details
Main Authors: Grzegorz M. Cech, Anna Kloska, Klaudyna Krause, Katarzyna Potrykus, Michael Cashel, Agnieszka Szalewska-Pałasz
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
P1<i>vir</i> bacteriophage
P1 phage
DksA
lytic development
host-virus interactions
Online Access:https://www.mdpi.com/1422-0067/22/11/5890

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