Primary Hepatic Small-Cell Carcinoma Developed during Antiviral Treatment for Chronic Hepatitis B

Previously reported cases of primary hepatic small-cell carcinoma were all detected at progressed state with associated symptoms. Therefore, the natural course of primary hepatic small-cell carcinoma remains unknown. This case shows the natural course of primary hepatic small-cell carcinoma. We dete...

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Main Author: Suk Bae Kim
Format: Article
Language:English
Published: Karger Publishers 2015-12-01
Series:Case Reports in Gastroenterology
Subjects:
Online Access:http://www.karger.com/Article/FullText/442462
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author Suk Bae Kim
author_facet Suk Bae Kim
author_sort Suk Bae Kim
collection DOAJ
description Previously reported cases of primary hepatic small-cell carcinoma were all detected at progressed state with associated symptoms. Therefore, the natural course of primary hepatic small-cell carcinoma remains unknown. This case shows the natural course of primary hepatic small-cell carcinoma. We detected a 1.2 cm hypodense nodule 6 months ago in a patient with cirrhosis who had been taking entecavir. It was suspected to be a regenerating or degenerating nodule. Three months later, liver computed tomography (CT) revealed that the mass was increased to 2.1 cm with the same characteristics. The patient wanted to do a follow-up CT scan after 3 months instead of a biopsy. Another 3 months later, the mass was markedly increased, involving the whole left lobe and was confirmed as small-cell carcinoma on biopsy. Here, we report the first case of primary hepatic small-cell carcinoma developed during treatment for chronic hepatitis B with cirrhosis.
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spelling doaj.art-61e1415b57da4be19cd8a1eb7523d6632022-12-21T19:07:28ZengKarger PublishersCase Reports in Gastroenterology1662-06312015-12-019337538010.1159/000442462442462Primary Hepatic Small-Cell Carcinoma Developed during Antiviral Treatment for Chronic Hepatitis BSuk Bae KimPreviously reported cases of primary hepatic small-cell carcinoma were all detected at progressed state with associated symptoms. Therefore, the natural course of primary hepatic small-cell carcinoma remains unknown. This case shows the natural course of primary hepatic small-cell carcinoma. We detected a 1.2 cm hypodense nodule 6 months ago in a patient with cirrhosis who had been taking entecavir. It was suspected to be a regenerating or degenerating nodule. Three months later, liver computed tomography (CT) revealed that the mass was increased to 2.1 cm with the same characteristics. The patient wanted to do a follow-up CT scan after 3 months instead of a biopsy. Another 3 months later, the mass was markedly increased, involving the whole left lobe and was confirmed as small-cell carcinoma on biopsy. Here, we report the first case of primary hepatic small-cell carcinoma developed during treatment for chronic hepatitis B with cirrhosis.http://www.karger.com/Article/FullText/442462LiverCirrhosisPrimary small-cell carcinomaChronic hepatitis B
spellingShingle Suk Bae Kim
Primary Hepatic Small-Cell Carcinoma Developed during Antiviral Treatment for Chronic Hepatitis B
Case Reports in Gastroenterology
Liver
Cirrhosis
Primary small-cell carcinoma
Chronic hepatitis B
title Primary Hepatic Small-Cell Carcinoma Developed during Antiviral Treatment for Chronic Hepatitis B
title_full Primary Hepatic Small-Cell Carcinoma Developed during Antiviral Treatment for Chronic Hepatitis B
title_fullStr Primary Hepatic Small-Cell Carcinoma Developed during Antiviral Treatment for Chronic Hepatitis B
title_full_unstemmed Primary Hepatic Small-Cell Carcinoma Developed during Antiviral Treatment for Chronic Hepatitis B
title_short Primary Hepatic Small-Cell Carcinoma Developed during Antiviral Treatment for Chronic Hepatitis B
title_sort primary hepatic small cell carcinoma developed during antiviral treatment for chronic hepatitis b
topic Liver
Cirrhosis
Primary small-cell carcinoma
Chronic hepatitis B
url http://www.karger.com/Article/FullText/442462
work_keys_str_mv AT sukbaekim primaryhepaticsmallcellcarcinomadevelopedduringantiviraltreatmentforchronichepatitisb