Visible Light-driven Photocatalytic Synthesis of Medium-sized Lactams with Graphitic Carbon Nitride as Catalyst
Medium-sized ring lactams have been found as key structures in various bioactive molecules, and they are of vital importance in natural or pharmaceutical molecule synthesis. In this work 9-membered-ring lactams were synthesized with graphitic carbon nitride (g-C3N4) as photocatalyst, BI-OAc as oxida...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Editorial Office of Journal of Taiyuan University of Technology
2022-07-01
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| Series: | Taiyuan Ligong Daxue xuebao |
| Subjects: | |
| Online Access: | https://tyutjournal.tyut.edu.cn/englishpaper/show-1896.html |
| _version_ | 1827283500312559616 |
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| author | Xin CUI Danyang HAO Wenjing YANG Zhen GUO |
| author_facet | Xin CUI Danyang HAO Wenjing YANG Zhen GUO |
| author_sort | Xin CUI |
| collection | DOAJ |
| description | Medium-sized ring lactams have been found as key structures in various bioactive molecules, and they are of vital importance in natural or pharmaceutical molecule synthesis. In this work 9-membered-ring lactams were synthesized with graphitic carbon nitride (g-C3N4) as photocatalyst, BI-OAc as oxidant under visible light in optimized mild conditions. These reactions exhibit a broad scope of substrates with good to excellent yield (up to 90%). In parallel, an amidyl-radical-involved photocatalytic ring expansion mechanism was proposed. This work paves a new way for the synthesis of medium-sized-ring molecules in a green and economical method. |
| first_indexed | 2024-04-24T09:36:24Z |
| format | Article |
| id | doaj.art-61e4c5fc38724a0abff7cf657c297665 |
| institution | Directory Open Access Journal |
| issn | 1007-9432 |
| language | English |
| last_indexed | 2024-04-24T09:36:24Z |
| publishDate | 2022-07-01 |
| publisher | Editorial Office of Journal of Taiyuan University of Technology |
| record_format | Article |
| series | Taiyuan Ligong Daxue xuebao |
| spelling | doaj.art-61e4c5fc38724a0abff7cf657c2976652024-04-15T09:15:45ZengEditorial Office of Journal of Taiyuan University of TechnologyTaiyuan Ligong Daxue xuebao1007-94322022-07-0153463563910.16355/j.cnki.issn1007-9432tyut.2022.04.0071007-9432(2022)04-0635-05Visible Light-driven Photocatalytic Synthesis of Medium-sized Lactams with Graphitic Carbon Nitride as CatalystXin CUI0Danyang HAO1Wenjing YANG2Zhen GUO3College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, ChinaCollege of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, ChinaCollege of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, ChinaCollege of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, ChinaMedium-sized ring lactams have been found as key structures in various bioactive molecules, and they are of vital importance in natural or pharmaceutical molecule synthesis. In this work 9-membered-ring lactams were synthesized with graphitic carbon nitride (g-C3N4) as photocatalyst, BI-OAc as oxidant under visible light in optimized mild conditions. These reactions exhibit a broad scope of substrates with good to excellent yield (up to 90%). In parallel, an amidyl-radical-involved photocatalytic ring expansion mechanism was proposed. This work paves a new way for the synthesis of medium-sized-ring molecules in a green and economical method.https://tyutjournal.tyut.edu.cn/englishpaper/show-1896.htmlphotocatalysisgraphitic carbon nitridelactamring expansion reaction |
| spellingShingle | Xin CUI Danyang HAO Wenjing YANG Zhen GUO Visible Light-driven Photocatalytic Synthesis of Medium-sized Lactams with Graphitic Carbon Nitride as Catalyst Taiyuan Ligong Daxue xuebao photocatalysis graphitic carbon nitride lactam ring expansion reaction |
| title | Visible Light-driven Photocatalytic Synthesis of Medium-sized Lactams with Graphitic Carbon Nitride as Catalyst |
| title_full | Visible Light-driven Photocatalytic Synthesis of Medium-sized Lactams with Graphitic Carbon Nitride as Catalyst |
| title_fullStr | Visible Light-driven Photocatalytic Synthesis of Medium-sized Lactams with Graphitic Carbon Nitride as Catalyst |
| title_full_unstemmed | Visible Light-driven Photocatalytic Synthesis of Medium-sized Lactams with Graphitic Carbon Nitride as Catalyst |
| title_short | Visible Light-driven Photocatalytic Synthesis of Medium-sized Lactams with Graphitic Carbon Nitride as Catalyst |
| title_sort | visible light driven photocatalytic synthesis of medium sized lactams with graphitic carbon nitride as catalyst |
| topic | photocatalysis graphitic carbon nitride lactam ring expansion reaction |
| url | https://tyutjournal.tyut.edu.cn/englishpaper/show-1896.html |
| work_keys_str_mv | AT xincui visiblelightdrivenphotocatalyticsynthesisofmediumsizedlactamswithgraphiticcarbonnitrideascatalyst AT danyanghao visiblelightdrivenphotocatalyticsynthesisofmediumsizedlactamswithgraphiticcarbonnitrideascatalyst AT wenjingyang visiblelightdrivenphotocatalyticsynthesisofmediumsizedlactamswithgraphiticcarbonnitrideascatalyst AT zhenguo visiblelightdrivenphotocatalyticsynthesisofmediumsizedlactamswithgraphiticcarbonnitrideascatalyst |