Myelin oligodendrocyte glycoprotein antibody-associated disease manifesting as intractable fever managed by bromocriptine: a case report
Background Demyelinating events expressed as abnormal thermoregulatory responses are rare, but intractable fever in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is very rarely reported. Case Report A 56-year-old woman presented with quadriparesis with acroparesthesia. Duri...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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The Korean Neurocritical Care Society
2023-06-01
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| Series: | Journal of Neurocritical Care |
| Subjects: | |
| Online Access: | http://e-jnc.org/upload/pdf/jnc-230020.pdf |
| _version_ | 1827913363276955648 |
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| author | Jin San Lee Sukyoon Lee Seong-il Oh |
| author_facet | Jin San Lee Sukyoon Lee Seong-il Oh |
| author_sort | Jin San Lee |
| collection | DOAJ |
| description | Background Demyelinating events expressed as abnormal thermoregulatory responses are rare, but intractable fever in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is very rarely reported. Case Report A 56-year-old woman presented with quadriparesis with acroparesthesia. During the admission, fever developed and persisted for 2 days despite the administration of high-dose antipyretics. Brain magnetic resonance imaging (MRI) showed hyperintense lesions involving the upper brainstem. A diagnosis of MOGAD was made according to the clinical characteristics and presence of seropositive MOG antibody. After administration of oral bromocriptine (2.5 mg/day), fever was slowly controlled for a few days. Conclusion The present case explained that persistent fever in MOGAD could manifest as an uncommon manifestation. The lesion in the upper brainstem within the brain MRI could be thought of as a lesion anterior to the periaqueductal gray and the lesion at that site could be the cause of the patient's persistent fever with unknown origin. |
| first_indexed | 2024-03-13T02:29:10Z |
| format | Article |
| id | doaj.art-61e629830ca244428cbf1253e3882671 |
| institution | Directory Open Access Journal |
| issn | 2005-0348 2508-1349 |
| language | English |
| last_indexed | 2024-03-13T02:29:10Z |
| publishDate | 2023-06-01 |
| publisher | The Korean Neurocritical Care Society |
| record_format | Article |
| series | Journal of Neurocritical Care |
| spelling | doaj.art-61e629830ca244428cbf1253e38826712023-06-30T01:45:00ZengThe Korean Neurocritical Care SocietyJournal of Neurocritical Care2005-03482508-13492023-06-01161434510.18700/jnc.230020391Myelin oligodendrocyte glycoprotein antibody-associated disease manifesting as intractable fever managed by bromocriptine: a case reportJin San Lee0Sukyoon Lee1Seong-il Oh2 Department of Neurology, Kyung Hee University Hospital, Seoul, Korea Department of Neurology, Inje University Busan Paik Hospital, Busan, Korea Department of Neurology, Kyung Hee University Hospital, Seoul, KoreaBackground Demyelinating events expressed as abnormal thermoregulatory responses are rare, but intractable fever in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is very rarely reported. Case Report A 56-year-old woman presented with quadriparesis with acroparesthesia. During the admission, fever developed and persisted for 2 days despite the administration of high-dose antipyretics. Brain magnetic resonance imaging (MRI) showed hyperintense lesions involving the upper brainstem. A diagnosis of MOGAD was made according to the clinical characteristics and presence of seropositive MOG antibody. After administration of oral bromocriptine (2.5 mg/day), fever was slowly controlled for a few days. Conclusion The present case explained that persistent fever in MOGAD could manifest as an uncommon manifestation. The lesion in the upper brainstem within the brain MRI could be thought of as a lesion anterior to the periaqueductal gray and the lesion at that site could be the cause of the patient's persistent fever with unknown origin.http://e-jnc.org/upload/pdf/jnc-230020.pdfmyelin oligodendrocyte glycoprotein antibody-associated diseasefeverencephalomyelitis |
| spellingShingle | Jin San Lee Sukyoon Lee Seong-il Oh Myelin oligodendrocyte glycoprotein antibody-associated disease manifesting as intractable fever managed by bromocriptine: a case report Journal of Neurocritical Care myelin oligodendrocyte glycoprotein antibody-associated disease fever encephalomyelitis |
| title | Myelin oligodendrocyte glycoprotein antibody-associated disease manifesting as intractable fever managed by bromocriptine: a case report |
| title_full | Myelin oligodendrocyte glycoprotein antibody-associated disease manifesting as intractable fever managed by bromocriptine: a case report |
| title_fullStr | Myelin oligodendrocyte glycoprotein antibody-associated disease manifesting as intractable fever managed by bromocriptine: a case report |
| title_full_unstemmed | Myelin oligodendrocyte glycoprotein antibody-associated disease manifesting as intractable fever managed by bromocriptine: a case report |
| title_short | Myelin oligodendrocyte glycoprotein antibody-associated disease manifesting as intractable fever managed by bromocriptine: a case report |
| title_sort | myelin oligodendrocyte glycoprotein antibody associated disease manifesting as intractable fever managed by bromocriptine a case report |
| topic | myelin oligodendrocyte glycoprotein antibody-associated disease fever encephalomyelitis |
| url | http://e-jnc.org/upload/pdf/jnc-230020.pdf |
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