1-(3-Amino-1-phenylpropyl)-3-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one

Starting from 1-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one (1) and (1-bromo-3-chloropropyl)benzene (2), the target compound 3, which represents a precursor for future radiolabeling, is prepared in a three-step synthesis.

Bibliographic Details
Main Authors: Catharina Neudorfer, Nadine Eberherr, Karem Shanab, Wolfgang Holzer, Christina Rami-Mark, Markus Mitterhauser, Wolfgang Wadsak, Helmut Spreitzer
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Molbank
Subjects:
Online Access:http://www.mdpi.com/1422-8599/2015/3/M867
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author Catharina Neudorfer
Nadine Eberherr
Karem Shanab
Wolfgang Holzer
Christina Rami-Mark
Markus Mitterhauser
Wolfgang Wadsak
Helmut Spreitzer
author_facet Catharina Neudorfer
Nadine Eberherr
Karem Shanab
Wolfgang Holzer
Christina Rami-Mark
Markus Mitterhauser
Wolfgang Wadsak
Helmut Spreitzer
author_sort Catharina Neudorfer
collection DOAJ
description Starting from 1-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one (1) and (1-bromo-3-chloropropyl)benzene (2), the target compound 3, which represents a precursor for future radiolabeling, is prepared in a three-step synthesis.
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spelling doaj.art-61e9b29bd4a8464ebb1cb5a96ecf591b2022-12-21T18:47:29ZengMDPI AGMolbank1422-85992015-08-0120153M86710.3390/M867M8671-(3-Amino-1-phenylpropyl)-3-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-oneCatharina Neudorfer0Nadine Eberherr1Karem Shanab2Wolfgang Holzer3Christina Rami-Mark4Markus Mitterhauser5Wolfgang Wadsak6Helmut Spreitzer7Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDivision of Drug Synthesis, Department of Pharmaceutical Chemistry, Faculty of Life Sciences, University of Vienna, Althanstraße 14, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDivision of Drug Synthesis, Department of Pharmaceutical Chemistry, Faculty of Life Sciences, University of Vienna, Althanstraße 14, 1090 Vienna, AustriaStarting from 1-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one (1) and (1-bromo-3-chloropropyl)benzene (2), the target compound 3, which represents a precursor for future radiolabeling, is prepared in a three-step synthesis.http://www.mdpi.com/1422-8599/2015/3/M867NET, PET, FAPPI
spellingShingle Catharina Neudorfer
Nadine Eberherr
Karem Shanab
Wolfgang Holzer
Christina Rami-Mark
Markus Mitterhauser
Wolfgang Wadsak
Helmut Spreitzer
1-(3-Amino-1-phenylpropyl)-3-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one
Molbank
NET, PET, FAPPI
title 1-(3-Amino-1-phenylpropyl)-3-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one
title_full 1-(3-Amino-1-phenylpropyl)-3-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one
title_fullStr 1-(3-Amino-1-phenylpropyl)-3-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one
title_full_unstemmed 1-(3-Amino-1-phenylpropyl)-3-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one
title_short 1-(3-Amino-1-phenylpropyl)-3-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one
title_sort 1 3 amino 1 phenylpropyl 3 2 fluorophenyl 1 3 dihydro 2h benzimidazol 2 one
topic NET, PET, FAPPI
url http://www.mdpi.com/1422-8599/2015/3/M867
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