Aldosterone: Essential for Life but Damaging to the Vascular Endothelium
The renin angiotensin aldosterone system is a key regulator of blood pressure. Aldosterone is the final effector of this pathway, acting predominantly via mineralocorticoid receptors. Aldosterone facilitates the conservation of sodium and, with it, water and acts as a powerful stimulus for potassium...
Main Authors: | Michael Crompton, Laura J. Skinner, Simon C. Satchell, Matthew J. Butler |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-06-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/13/6/1004 |
Similar Items
-
Mineralocorticoid Receptor-Dependent Impairment of Baroreflex Contributes to Hypertension in a Mouse Model of Primary Aldosteronism
by: Luo Shi, et al.
Published: (2019-11-01) -
Effects of chronically high levels of aldosterone on different cognitive dimensions: an investigation in patients with primary aldosteronism
by: Lukas Engler, et al.
Published: (2019-04-01) -
Effects of Chronic Kidney Disease on Nanomechanics of the Endothelial Glycocalyx Are Mediated by the Mineralocorticoid Receptor
by: Benedikt Fels, et al.
Published: (2022-09-01) -
Adverse Effects of Aldosterone: Beyond Blood Pressure
by: Jenifer M. Brown
Published: (2024-04-01) -
Correlation of functional and radioligand binding characteristics of GPER ligands confirming aldosterone as a GPER agonist
by: Qingming Ding, et al.
Published: (2022-10-01)