Longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction.
<h4>Objective</h4>Unfavorable blood lipid profiles are robust risk factors in predicting atherosclerotic disease. Studies have shown that positive affect (PA) is associated with a favorable lipid profile. However, longitudinal studies regarding the course of PA and lipid profiles in myoc...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287166&type=printable |
| _version_ | 1797633205213331456 |
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| author | Mary Princip Roland von Känel Sinthujan Sivakumar Lena Jellestad Aju P Pazhenkottil Rebecca E Langraf-Meister Hansjörg Znoj Jean-Paul Schmid Jürgen Barth Ulrich Schnyder Claudia Zuccarella-Hackl |
| author_facet | Mary Princip Roland von Känel Sinthujan Sivakumar Lena Jellestad Aju P Pazhenkottil Rebecca E Langraf-Meister Hansjörg Znoj Jean-Paul Schmid Jürgen Barth Ulrich Schnyder Claudia Zuccarella-Hackl |
| author_sort | Mary Princip |
| collection | DOAJ |
| description | <h4>Objective</h4>Unfavorable blood lipid profiles are robust risk factors in predicting atherosclerotic disease. Studies have shown that positive affect (PA) is associated with a favorable lipid profile. However, longitudinal studies regarding the course of PA and lipid profiles in myocardial infarction (MI) patients are lacking. Therefore, the aim of this study was to prospectively explore the association between PA and blood lipid levels across three inv estigations over 12 months following acute MI.<h4>Methods</h4>Patients following an acute MI were examined at hospital admission (n = 190), and at 3 months (n = 154) and 12 months (n = 106) thereafter. Linear mixed effect regression models were used to evaluate the relation between PA, assessed with the Global Mood Scale, and blood lipid levels. Potential confounding variables were controlled for in the analysis.<h4>Results</h4>Higher PA was significantly associated with higher high-density lipoprotein cholesterol (HDL-C) levels and a lower total cholesterol (TC)/HDL-C ratio over time, independent of demographic factors, indices of cardiac disease severity, comorbidity, medication use, health behaviors, serum cortisol and negative affect (p≤0.040). No association was found between PA and the two blood lipids low-density lipoprotein-cholesterol (LDL-C) and triglycerides (TG).<h4>Conclusions</h4>Positive affect was independently associated with HDL-C levels and the TC/HDL-C ratio in patients up to 1 year after MI. The findings support a potential role of PA for cardiovascular health through an association with a favorable blood lipid profile. |
| first_indexed | 2024-03-11T11:50:48Z |
| format | Article |
| id | doaj.art-61ec977cdc8a43fcb76ca14ea8511c56 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-03-11T11:50:48Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-61ec977cdc8a43fcb76ca14ea8511c562023-11-09T05:32:23ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-011811e028716610.1371/journal.pone.0287166Longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction.Mary PrincipRoland von KänelSinthujan SivakumarLena JellestadAju P PazhenkottilRebecca E Langraf-MeisterHansjörg ZnojJean-Paul SchmidJürgen BarthUlrich SchnyderClaudia Zuccarella-Hackl<h4>Objective</h4>Unfavorable blood lipid profiles are robust risk factors in predicting atherosclerotic disease. Studies have shown that positive affect (PA) is associated with a favorable lipid profile. However, longitudinal studies regarding the course of PA and lipid profiles in myocardial infarction (MI) patients are lacking. Therefore, the aim of this study was to prospectively explore the association between PA and blood lipid levels across three inv estigations over 12 months following acute MI.<h4>Methods</h4>Patients following an acute MI were examined at hospital admission (n = 190), and at 3 months (n = 154) and 12 months (n = 106) thereafter. Linear mixed effect regression models were used to evaluate the relation between PA, assessed with the Global Mood Scale, and blood lipid levels. Potential confounding variables were controlled for in the analysis.<h4>Results</h4>Higher PA was significantly associated with higher high-density lipoprotein cholesterol (HDL-C) levels and a lower total cholesterol (TC)/HDL-C ratio over time, independent of demographic factors, indices of cardiac disease severity, comorbidity, medication use, health behaviors, serum cortisol and negative affect (p≤0.040). No association was found between PA and the two blood lipids low-density lipoprotein-cholesterol (LDL-C) and triglycerides (TG).<h4>Conclusions</h4>Positive affect was independently associated with HDL-C levels and the TC/HDL-C ratio in patients up to 1 year after MI. The findings support a potential role of PA for cardiovascular health through an association with a favorable blood lipid profile.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287166&type=printable |
| spellingShingle | Mary Princip Roland von Känel Sinthujan Sivakumar Lena Jellestad Aju P Pazhenkottil Rebecca E Langraf-Meister Hansjörg Znoj Jean-Paul Schmid Jürgen Barth Ulrich Schnyder Claudia Zuccarella-Hackl Longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction. PLoS ONE |
| title | Longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction. |
| title_full | Longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction. |
| title_fullStr | Longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction. |
| title_full_unstemmed | Longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction. |
| title_short | Longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction. |
| title_sort | longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287166&type=printable |
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