SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis
Metastatic disease is the major reason for breast cancer-related deaths; therefore, a better understanding of this process and its players is needed. Here the authors report the role of SIRT7 in inhibiting SMAD4-mediated breast cancer metastasis providing a possible therapeutic avenue.
Bibliografiske detaljer
| Main Authors: |
Xiaolong Tang,
Lei Shi,
Ni Xie,
Zuojun Liu,
Minxian Qian,
Fanbiao Meng,
Qingyang Xu,
Mingyan Zhou,
Xinyue Cao,
Wei-Guo Zhu,
Baohua Liu |
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| Format: | Article
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| Sprog: | English |
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| Udgivet: |
Nature Portfolio
2017-08-01
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| Serier: | Nature Communications
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| Online adgang: | https://doi.org/10.1038/s41467-017-00396-9
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