Immense Tumor of Maxillary Sinus with Exophthalmos—A Rare Underlying Cause
Sinus tumors are arduous to diagnose due to often prolonging asymptomatic course until the infiltration of the adjacent structures occurs. Therefore, patients are diagnosed with advanced-stage disease, which negatively affects the treatment outcomes. A 60-year-old male was referred to our ward from...
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| Format: | Article |
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MDPI AG
2022-10-01
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| Series: | Hematology Reports |
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| Online Access: | https://www.mdpi.com/2038-8330/14/4/44 |
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| author | Olga Lesniewska-Skowerska Joanna Symela-Kaspera Lucyna Klimczak-Gołąb Wojciech Smolka Jaroslaw Markowski |
| author_facet | Olga Lesniewska-Skowerska Joanna Symela-Kaspera Lucyna Klimczak-Gołąb Wojciech Smolka Jaroslaw Markowski |
| author_sort | Olga Lesniewska-Skowerska |
| collection | DOAJ |
| description | Sinus tumors are arduous to diagnose due to often prolonging asymptomatic course until the infiltration of the adjacent structures occurs. Therefore, patients are diagnosed with advanced-stage disease, which negatively affects the treatment outcomes. A 60-year-old male was referred to our ward from an outpatient clinic. The patient presented with double vision, right-side lacrimation, and exophthalmos. He also reported significant weight loss: 15 kg in 2 months. Physical examination revealed achiness and edema of the right temporal area, and subconjunctival hemorrhage of the right eye, and surprisingly no anosmia, no nasal obstruction, and no head/neck lymphadenopathy were present. The histopathology examination identified diffuse large B-cell lymphoma (CD20+ CD3- p63- bcl-2+ CD23-/+ bcl-6+ CD 10- MUM1+ Tdt- CD38- cyclin D1- CD30- c-myc+). The patient was qualified for R-CHOP immunochemotherapy (rituximab, cyclophosphamide, and hydroxydaunorubicin hydrochloride), which was well tolerated. After 3 months of treatment, all of the symptoms reversed and a whole-body PET scan showed no abnormal metabolic activity. |
| first_indexed | 2024-03-09T16:21:41Z |
| format | Article |
| id | doaj.art-61edcae41ac548b4883ce02307282773 |
| institution | Directory Open Access Journal |
| issn | 2038-8330 |
| language | English |
| last_indexed | 2024-03-09T16:21:41Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Hematology Reports |
| spelling | doaj.art-61edcae41ac548b4883ce023072827732023-11-24T15:12:57ZengMDPI AGHematology Reports2038-83302022-10-0114430530910.3390/hematolrep14040044Immense Tumor of Maxillary Sinus with Exophthalmos—A Rare Underlying CauseOlga Lesniewska-Skowerska0Joanna Symela-Kaspera1Lucyna Klimczak-Gołąb2Wojciech Smolka3Jaroslaw Markowski4Department of Laryngology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, PolandDepartment of Laryngology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, PolandDepartment of Laryngology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, PolandDepartment of Laryngology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, PolandDepartment of Laryngology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, PolandSinus tumors are arduous to diagnose due to often prolonging asymptomatic course until the infiltration of the adjacent structures occurs. Therefore, patients are diagnosed with advanced-stage disease, which negatively affects the treatment outcomes. A 60-year-old male was referred to our ward from an outpatient clinic. The patient presented with double vision, right-side lacrimation, and exophthalmos. He also reported significant weight loss: 15 kg in 2 months. Physical examination revealed achiness and edema of the right temporal area, and subconjunctival hemorrhage of the right eye, and surprisingly no anosmia, no nasal obstruction, and no head/neck lymphadenopathy were present. The histopathology examination identified diffuse large B-cell lymphoma (CD20+ CD3- p63- bcl-2+ CD23-/+ bcl-6+ CD 10- MUM1+ Tdt- CD38- cyclin D1- CD30- c-myc+). The patient was qualified for R-CHOP immunochemotherapy (rituximab, cyclophosphamide, and hydroxydaunorubicin hydrochloride), which was well tolerated. After 3 months of treatment, all of the symptoms reversed and a whole-body PET scan showed no abnormal metabolic activity.https://www.mdpi.com/2038-8330/14/4/44lympomasinusmaxillarytumor |
| spellingShingle | Olga Lesniewska-Skowerska Joanna Symela-Kaspera Lucyna Klimczak-Gołąb Wojciech Smolka Jaroslaw Markowski Immense Tumor of Maxillary Sinus with Exophthalmos—A Rare Underlying Cause Hematology Reports lympoma sinus maxillary tumor |
| title | Immense Tumor of Maxillary Sinus with Exophthalmos—A Rare Underlying Cause |
| title_full | Immense Tumor of Maxillary Sinus with Exophthalmos—A Rare Underlying Cause |
| title_fullStr | Immense Tumor of Maxillary Sinus with Exophthalmos—A Rare Underlying Cause |
| title_full_unstemmed | Immense Tumor of Maxillary Sinus with Exophthalmos—A Rare Underlying Cause |
| title_short | Immense Tumor of Maxillary Sinus with Exophthalmos—A Rare Underlying Cause |
| title_sort | immense tumor of maxillary sinus with exophthalmos a rare underlying cause |
| topic | lympoma sinus maxillary tumor |
| url | https://www.mdpi.com/2038-8330/14/4/44 |
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