Soya-cerebroside reduces IL-1β-induced MMP-1 production in chondrocytes and inhibits cartilage degradation: implications for the treatment of osteoarthritis

Soya-cerebroside reduces IL-1β-induced MMP-1 production in chondrocytes and inhibits cartilage degradation: implications for the treatment of osteoarthritis

Osteoarthritis (OA) commonly affects the synovial joint and is characterized by degradation of articular cartilage, which is largely mobilized by increased matrix metalloproteinase (MMP) activity. Soya-cerebroside, an extract of Cordyceps militaris, inhibits inflammatory cytokine production and mono...

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Bibliographic Details
Main Authors: Shan-Chi Liu, Chun-Hao Tsai, Tung-Ying Wu, Chang-Hai Tsai, Fuu-Jen Tsai, Jing-Gung Chung, Chih-Yang Huang, Jai-Sing Yang, Yuan-Man Hsu, Mei-Chin Yin, Yang-Chang Wu, Chih-Hsin Tang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Food and Agricultural Immunology
Subjects:
soya-cerebroside
osteoarthritis
chondrocytes
il-1β
mmp-1
Online Access:http://dx.doi.org/10.1080/09540105.2019.1611745

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