Impact of Thin Meconium on Delivery and Early Neonatal Outcomes
Several reports regarding the effects of thin meconium on maternal and neonatal outcomes are contradictory. This study evaluated the risk factors and obstetrical outcomes during deliveries complicated with thin meconium. This retrospective cohort study included all women with a singleton pregnancy,...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/10/2/215 |
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| author | Hanoch Schreiber Adi Shilony Reut Batia Amrami Gal Cohen Ofer Markovitch Tal Biron-Shental Sofia Bauer-Rusek Shmuel Arnon Michal Kovo |
| author_facet | Hanoch Schreiber Adi Shilony Reut Batia Amrami Gal Cohen Ofer Markovitch Tal Biron-Shental Sofia Bauer-Rusek Shmuel Arnon Michal Kovo |
| author_sort | Hanoch Schreiber |
| collection | DOAJ |
| description | Several reports regarding the effects of thin meconium on maternal and neonatal outcomes are contradictory. This study evaluated the risk factors and obstetrical outcomes during deliveries complicated with thin meconium. This retrospective cohort study included all women with a singleton pregnancy, who underwent trial of labor >24 weeks of gestation, in a single tertiary center, over a six-year period. Obstetrical, delivery, and neonatal outcomes were compared between deliveries with thin meconium (thin meconium group) to deliveries with clear amniotic fluid (control group). Included in the study were 31,536 deliveries. Among them 1946 (6.2%) were in the thin meconium group and 29,590 (93.8%) were controls. Meconium aspiration syndrome was diagnosed in eight neonates in the thin meconium group and in none of the controls (0.41%, <i>p</i> < 0.001). In multivariate logistic regression analysis, the following adverse outcomes were found to be independently associated with increased odds ratio (OR) for thin meconium: intrapartum fever (OR 1.37, 95% CI 1.1–1.7), instrumental delivery (OR 1.26, 95% CI 1.09–1.46), cesarean delivery for non-reassuring fetal heart rate (OR 2.0, 95% CI 1.68–2.46), and respiratory distress requiring mechanical ventilation (OR 2.06, 95% CI 1.19–3.56). Thin meconium was associated with adverse obstetrical, delivery, and neonatal outcomes that should receive extra neonatal care and alert the pediatrician. |
| first_indexed | 2024-03-11T08:59:55Z |
| format | Article |
| id | doaj.art-61fd1a60f0b4436798e838e87f4b8b96 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-11T08:59:55Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-61fd1a60f0b4436798e838e87f4b8b962023-11-16T19:47:38ZengMDPI AGChildren2227-90672023-01-0110221510.3390/children10020215Impact of Thin Meconium on Delivery and Early Neonatal OutcomesHanoch Schreiber0Adi Shilony1Reut Batia Amrami2Gal Cohen3Ofer Markovitch4Tal Biron-Shental5Sofia Bauer-Rusek6Shmuel Arnon7Michal Kovo8Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba 4428163, IsraelDepartment of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba 4428163, IsraelDepartment of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba 4428163, IsraelDepartment of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba 4428163, IsraelDepartment of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba 4428163, IsraelDepartment of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba 4428163, IsraelSackler School of Medicine, Tel Aviv University, Tel Aviv 6329302, IsraelSackler School of Medicine, Tel Aviv University, Tel Aviv 6329302, IsraelDepartment of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba 4428163, IsraelSeveral reports regarding the effects of thin meconium on maternal and neonatal outcomes are contradictory. This study evaluated the risk factors and obstetrical outcomes during deliveries complicated with thin meconium. This retrospective cohort study included all women with a singleton pregnancy, who underwent trial of labor >24 weeks of gestation, in a single tertiary center, over a six-year period. Obstetrical, delivery, and neonatal outcomes were compared between deliveries with thin meconium (thin meconium group) to deliveries with clear amniotic fluid (control group). Included in the study were 31,536 deliveries. Among them 1946 (6.2%) were in the thin meconium group and 29,590 (93.8%) were controls. Meconium aspiration syndrome was diagnosed in eight neonates in the thin meconium group and in none of the controls (0.41%, <i>p</i> < 0.001). In multivariate logistic regression analysis, the following adverse outcomes were found to be independently associated with increased odds ratio (OR) for thin meconium: intrapartum fever (OR 1.37, 95% CI 1.1–1.7), instrumental delivery (OR 1.26, 95% CI 1.09–1.46), cesarean delivery for non-reassuring fetal heart rate (OR 2.0, 95% CI 1.68–2.46), and respiratory distress requiring mechanical ventilation (OR 2.06, 95% CI 1.19–3.56). Thin meconium was associated with adverse obstetrical, delivery, and neonatal outcomes that should receive extra neonatal care and alert the pediatrician.https://www.mdpi.com/2227-9067/10/2/215meconiumthin meconiummeconium aspiration syndromeadverse neonatal outcomes |
| spellingShingle | Hanoch Schreiber Adi Shilony Reut Batia Amrami Gal Cohen Ofer Markovitch Tal Biron-Shental Sofia Bauer-Rusek Shmuel Arnon Michal Kovo Impact of Thin Meconium on Delivery and Early Neonatal Outcomes Children meconium thin meconium meconium aspiration syndrome adverse neonatal outcomes |
| title | Impact of Thin Meconium on Delivery and Early Neonatal Outcomes |
| title_full | Impact of Thin Meconium on Delivery and Early Neonatal Outcomes |
| title_fullStr | Impact of Thin Meconium on Delivery and Early Neonatal Outcomes |
| title_full_unstemmed | Impact of Thin Meconium on Delivery and Early Neonatal Outcomes |
| title_short | Impact of Thin Meconium on Delivery and Early Neonatal Outcomes |
| title_sort | impact of thin meconium on delivery and early neonatal outcomes |
| topic | meconium thin meconium meconium aspiration syndrome adverse neonatal outcomes |
| url | https://www.mdpi.com/2227-9067/10/2/215 |
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