Visible-Light-Enhanced Antibacterial Activity of Silver and Copper Co-Doped Titania Formed on Titanium via Chemical and Thermal Treatments
Dental implants made of titanium (Ti) are used in dentistry, but peri-implantitis is a serious associated problem. Antibacterial and osteoconductive Ti dental implants may decrease the risk of peri-implantitis. In this study, titania (TiO<sub>2</sub>) co-doped with silver (Ag) at 2.5 at....
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/2/650 |
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| author | Kanae Suzuki Misato Iwatsu Takayuki Mokudai Maiko Furuya Kotone Yokota Hiroyasu Kanetaka Masaya Shimabukuro Taishi Yokoi Masakazu Kawashita |
| author_facet | Kanae Suzuki Misato Iwatsu Takayuki Mokudai Maiko Furuya Kotone Yokota Hiroyasu Kanetaka Masaya Shimabukuro Taishi Yokoi Masakazu Kawashita |
| author_sort | Kanae Suzuki |
| collection | DOAJ |
| description | Dental implants made of titanium (Ti) are used in dentistry, but peri-implantitis is a serious associated problem. Antibacterial and osteoconductive Ti dental implants may decrease the risk of peri-implantitis. In this study, titania (TiO<sub>2</sub>) co-doped with silver (Ag) at 2.5 at.% and copper (Cu) at 4.9 at.% was formed on Ti substrates via chemical and thermal treatments. The Ag and Cu co-doped TiO<sub>2</sub> formed apatite in a simulated body fluid, which suggests osteoconductivity. It also showed antibacterial activity against <i>Escherichia coli</i>, which was enhanced by visible-light irradiation. This enhancement might be caused by the synergistic effect of the release of Ag and Cu and the generation of •OH from the sample. Dental implants with such a Ag and Cu co-doped TiO<sub>2</sub> formed on their surface may reduce the risk of peri-implantitis. |
| first_indexed | 2024-03-09T11:35:53Z |
| format | Article |
| id | doaj.art-61fd5d3d4ee4432b915a762aa0fe1cb5 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T11:35:53Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-61fd5d3d4ee4432b915a762aa0fe1cb52023-11-30T23:42:50ZengMDPI AGMolecules1420-30492023-01-0128265010.3390/molecules28020650Visible-Light-Enhanced Antibacterial Activity of Silver and Copper Co-Doped Titania Formed on Titanium via Chemical and Thermal TreatmentsKanae Suzuki0Misato Iwatsu1Takayuki Mokudai2Maiko Furuya3Kotone Yokota4Hiroyasu Kanetaka5Masaya Shimabukuro6Taishi Yokoi7Masakazu Kawashita8Graduate School of Biomedical Engineering, Tohoku University, 6-6-12 Aramaki-Aoba, Aoba-ku, Sendai 980-8579, JapanGraduate School of Dentistry, Tohoku University, 4-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, JapanInstitute of Materials Research, Tohoku University, 2-1-1, Katahira, Aoba-ku, Sendai 980-8577, JapanGraduate School of Dentistry, Tohoku University, 4-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, JapanGraduate School of Dentistry, Tohoku University, 4-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, JapanGraduate School of Dentistry, Tohoku University, 4-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, JapanInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-surugadai, Chiyoda-ku, Tokyo 101-0062, JapanInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-surugadai, Chiyoda-ku, Tokyo 101-0062, JapanInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-surugadai, Chiyoda-ku, Tokyo 101-0062, JapanDental implants made of titanium (Ti) are used in dentistry, but peri-implantitis is a serious associated problem. Antibacterial and osteoconductive Ti dental implants may decrease the risk of peri-implantitis. In this study, titania (TiO<sub>2</sub>) co-doped with silver (Ag) at 2.5 at.% and copper (Cu) at 4.9 at.% was formed on Ti substrates via chemical and thermal treatments. The Ag and Cu co-doped TiO<sub>2</sub> formed apatite in a simulated body fluid, which suggests osteoconductivity. It also showed antibacterial activity against <i>Escherichia coli</i>, which was enhanced by visible-light irradiation. This enhancement might be caused by the synergistic effect of the release of Ag and Cu and the generation of •OH from the sample. Dental implants with such a Ag and Cu co-doped TiO<sub>2</sub> formed on their surface may reduce the risk of peri-implantitis.https://www.mdpi.com/1420-3049/28/2/650titaniasilvercopperantibacterial activityvisible-light-responsive photocatalysis |
| spellingShingle | Kanae Suzuki Misato Iwatsu Takayuki Mokudai Maiko Furuya Kotone Yokota Hiroyasu Kanetaka Masaya Shimabukuro Taishi Yokoi Masakazu Kawashita Visible-Light-Enhanced Antibacterial Activity of Silver and Copper Co-Doped Titania Formed on Titanium via Chemical and Thermal Treatments Molecules titania silver copper antibacterial activity visible-light-responsive photocatalysis |
| title | Visible-Light-Enhanced Antibacterial Activity of Silver and Copper Co-Doped Titania Formed on Titanium via Chemical and Thermal Treatments |
| title_full | Visible-Light-Enhanced Antibacterial Activity of Silver and Copper Co-Doped Titania Formed on Titanium via Chemical and Thermal Treatments |
| title_fullStr | Visible-Light-Enhanced Antibacterial Activity of Silver and Copper Co-Doped Titania Formed on Titanium via Chemical and Thermal Treatments |
| title_full_unstemmed | Visible-Light-Enhanced Antibacterial Activity of Silver and Copper Co-Doped Titania Formed on Titanium via Chemical and Thermal Treatments |
| title_short | Visible-Light-Enhanced Antibacterial Activity of Silver and Copper Co-Doped Titania Formed on Titanium via Chemical and Thermal Treatments |
| title_sort | visible light enhanced antibacterial activity of silver and copper co doped titania formed on titanium via chemical and thermal treatments |
| topic | titania silver copper antibacterial activity visible-light-responsive photocatalysis |
| url | https://www.mdpi.com/1420-3049/28/2/650 |
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