Efficacy and Safety of Myrtol® Standardized in the Treatment of Acute and Chronic Rhinosinusitis: A Review of Literature

The clinical pattern of rhinosinusitis is based on key symptoms, such as nasal obstruction/congestion, nasal secretion with postnasal discharge, facial pain with pressure, and impaired sense of smell. Acute rhinosinusitis is a viral infection commonly caused by impaired paranasal sinus aeration and...

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Main Authors: Aleksandar Peric, Tanja Kosak Soklic, Aleksandra Aleksic, Gabriela Kopacheva-Barsova, Aneta V. Peric
Format: Article
Language:English
Published: KARE Publishing 2020-12-01
Series:Erciyes Medical Journal
Subjects:
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=erciyesmedj&un=EMJ-34467
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author Aleksandar Peric
Tanja Kosak Soklic
Aleksandra Aleksic
Gabriela Kopacheva-Barsova
Aneta V. Peric
author_facet Aleksandar Peric
Tanja Kosak Soklic
Aleksandra Aleksic
Gabriela Kopacheva-Barsova
Aneta V. Peric
author_sort Aleksandar Peric
collection DOAJ
description The clinical pattern of rhinosinusitis is based on key symptoms, such as nasal obstruction/congestion, nasal secretion with postnasal discharge, facial pain with pressure, and impaired sense of smell. Acute rhinosinusitis is a viral infection commonly caused by impaired paranasal sinus aeration and drainage and can progress to bacterial superinfection. Chronic rhinosinusitis is an inflammatory disease of the sinonasal mucosa with symptoms persisting for more than 12 weeks. This paper aimed to summarize and update the literature related to the use of herbal product Myrtol® standardized in the treatment of acute and chronic rhinosinusitis. Earlier investigations have demonstrated that Myrtol® standardized has strong secretolytic, secretomotoric, anti-inflammatory, antioxidative, and antimicrobial effects. Therefore, this study reviewed randomized studies related to its use in the treatment of upper-airway inflammations and discussed the mechanisms of action of this herbal drug on infected nasal and paranasal sinuses mucosa.
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spelling doaj.art-6200a2c9aa9e4f238533dce6354c11512023-02-15T16:11:59ZengKARE PublishingErciyes Medical Journal2149-22472020-12-014313810.14744/etd.2020.34467EMJ-34467Efficacy and Safety of Myrtol® Standardized in the Treatment of Acute and Chronic Rhinosinusitis: A Review of LiteratureAleksandar Peric0Tanja Kosak Soklic1Aleksandra Aleksic2Gabriela Kopacheva-Barsova3Aneta V. Peric4Department of Otorhinolaryngology, Military Medical Academy Faculty of Medicine, University of Defence, Belgrade, Serbia; MediGroup General Hospital, Milutina Milankovića, Belgrade, SerbiaDepartment of Otorhinolaryngology and Head and Neck Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, SloveniaClinical Centre of the Republic of Srpska, Faculty of Medicine, University of Banja Luka, Banja Luka, Bosnia and HerzegovinaENT University Clinic, University Campus 'St. Mother Theresa', Skopje, Republic of North MacedoniaInstitute for Pharmacy, Military Medical Academy, Faculty of Medicine, University of Defence, Crnotravska, Belgrade, SerbiaThe clinical pattern of rhinosinusitis is based on key symptoms, such as nasal obstruction/congestion, nasal secretion with postnasal discharge, facial pain with pressure, and impaired sense of smell. Acute rhinosinusitis is a viral infection commonly caused by impaired paranasal sinus aeration and drainage and can progress to bacterial superinfection. Chronic rhinosinusitis is an inflammatory disease of the sinonasal mucosa with symptoms persisting for more than 12 weeks. This paper aimed to summarize and update the literature related to the use of herbal product Myrtol® standardized in the treatment of acute and chronic rhinosinusitis. Earlier investigations have demonstrated that Myrtol® standardized has strong secretolytic, secretomotoric, anti-inflammatory, antioxidative, and antimicrobial effects. Therefore, this study reviewed randomized studies related to its use in the treatment of upper-airway inflammations and discussed the mechanisms of action of this herbal drug on infected nasal and paranasal sinuses mucosa.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=erciyesmedj&un=EMJ-34467sinusitisrhinitisherbal medicineplantsmedicinal
spellingShingle Aleksandar Peric
Tanja Kosak Soklic
Aleksandra Aleksic
Gabriela Kopacheva-Barsova
Aneta V. Peric
Efficacy and Safety of Myrtol® Standardized in the Treatment of Acute and Chronic Rhinosinusitis: A Review of Literature
Erciyes Medical Journal
sinusitis
rhinitis
herbal medicine
plants
medicinal
title Efficacy and Safety of Myrtol® Standardized in the Treatment of Acute and Chronic Rhinosinusitis: A Review of Literature
title_full Efficacy and Safety of Myrtol® Standardized in the Treatment of Acute and Chronic Rhinosinusitis: A Review of Literature
title_fullStr Efficacy and Safety of Myrtol® Standardized in the Treatment of Acute and Chronic Rhinosinusitis: A Review of Literature
title_full_unstemmed Efficacy and Safety of Myrtol® Standardized in the Treatment of Acute and Chronic Rhinosinusitis: A Review of Literature
title_short Efficacy and Safety of Myrtol® Standardized in the Treatment of Acute and Chronic Rhinosinusitis: A Review of Literature
title_sort efficacy and safety of myrtol r standardized in the treatment of acute and chronic rhinosinusitis a review of literature
topic sinusitis
rhinitis
herbal medicine
plants
medicinal
url https://jag.journalagent.com/z4/download_fulltext.asp?pdir=erciyesmedj&un=EMJ-34467
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