Integration of single-cell RNA sequencing and spatial transcriptomics to reveal the glioblastoma heterogeneity [version 1; peer review: 2 approved, 1 approved with reservations]

Integration of single-cell RNA sequencing and spatial transcriptomics to reveal the glioblastoma heterogeneity [version 1; peer review: 2 approved, 1 approved with reservations]

Glioblastoma (GBM), a deadly brain tumor, is still one of the few lasting challenges of contemporary oncology. Current therapies fail to significantly improve patient survival due to GBM’s tremendous genetic, transcriptomic, immunological, and sex-dependent heterogeneity. Over the years, clinical di...

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Bibliographic Details
Main Authors: Bozena Kaminska, Urszula Lawrynowicz, Monika Horbacz, Jakub Mieczkowski, Adrian Perdyan
Format: Article
Language:English
Published: F1000 Research Ltd 2022-10-01
Series:F1000Research
Subjects:
single-cell RNA sequencing
spatial transcriptomics
glioblastoma
heterogeneity
immunology
sex
eng
Online Access:https://f1000research.com/articles/11-1180/v1

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