Application of mini-pigs as a model for developing new methods of ischemic heart disease (IHD) treatment

At the last 30 years the application of the new laboratory species mini-pigs is progressively increasing in medical and biological research of atherosclerosis and other disorders of cardiovascular system. Mini-pigs differ from traditional experimental animals in maximal similarity of their anatomy...

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Bibliographic Details
Main Authors: V. N. Tikhonov, P. M. Larionov, A. V. Tikhonov
Format: Article
Language:Russian
Published: Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics 2010-12-01
Series:Атеросклероз
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Online Access:https://ateroskleroz.elpub.ru/jour/article/view/589/532
Description
Summary:At the last 30 years the application of the new laboratory species mini-pigs is progressively increasing in medical and biological research of atherosclerosis and other disorders of cardiovascular system. Mini-pigs differ from traditional experimental animals in maximal similarity of their anatomy and physiological functions of cardiovascular, digestive, excretory, and nervous systems with human ones. In the Institute of Cytology and Genetics SB RAS the specialized laboratory mini- and micro-pigs adapted for using under our conditions were created. In 2010 several hundreds of studies on mini-pigs were conducted in Russian Federation and abroad. The present review highlights some experimental works that could be applied for wide use in medicine.
ISSN:2078-256X