Prostaglandin Transporter and Dipeptidyl Peptidase-4 as New Pharmacological Targets in the Prevention of Acute Kidney Injury in Diabetes: An In Vitro Study

Prostaglandin Transporter and Dipeptidyl Peptidase-4 as New Pharmacological Targets in the Prevention of Acute Kidney Injury in Diabetes: An In Vitro Study

The probability of acute kidney injury (AKI) is higher in septic diabetic patients, which is associated with, among other factors, proximal tubular cell (PTC) injury induced by the hypoxic/hyperglycemic/inflammatory microenvironment that surrounds PTCs in these patients. Here, we exposed human PTCs...

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Bibliographic Details
Main Authors: Beatriz Gallego-Tamayo, Ángela Santos-Aparicio, Julia Yago-Ibáñez, Laura Muñoz-Moreno, Francisco Javier Lucio-Cazaña, Ana B. Fernández-Martínez
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
acute kidney injury
cyclo-oxygenase-2
diabetes mellitus
dipeptidyl peptidase-4
prostaglandin E2
prostaglandin transporter
Online Access:https://www.mdpi.com/1422-0067/25/6/3345

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