Scrub typhus in pregnancy - A threat to maternal and fetal outcome
Background and Objectives: Scrub typhus is an acute febrile illness transmitted by the bite of trombiculid mite in the larval stage. Scrub typhus is rare in pregnancy and there is paucity of data on the clinical outcome of scrub typhus during pregnancy. Material and Methods: We present five cases of...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2024;volume=13;issue=2;spage=764;epage=767;aulast=Bahadur |
| _version_ | 1827309404581527552 |
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| author | Anupama Bahadur Rajlaxmi Mundhra Anjali Pathak Mukesh Kumar Shri Ram Rundla Gayatri Suresh |
| author_facet | Anupama Bahadur Rajlaxmi Mundhra Anjali Pathak Mukesh Kumar Shri Ram Rundla Gayatri Suresh |
| author_sort | Anupama Bahadur |
| collection | DOAJ |
| description | Background and Objectives: Scrub typhus is an acute febrile illness transmitted by the bite of trombiculid mite in the larval stage. Scrub typhus is rare in pregnancy and there is paucity of data on the clinical outcome of scrub typhus during pregnancy. Material and Methods: We present five cases of scrub typhus complicating pregnancy who were admitted in the obstetric ward at AIIMS Rishikesh, India during the antenatal period for management. Results: The first patient presented at term pregnancy in semiconscious state while the rest were preterm between 31 and 34 weeks period of gestation. The age at presentation was 21–31 years. All five had febrile illness of >5 days' duration along with cough. Fever investigations like blood culture, peripheral smear for malarial parasite, dengue serology, widal test, and urine culture were negative. Serology for scrub typhus was positive in all. Once diagnosis was confirmed for scrub typhus, patients were given the drug of choice azithromycin 500 mg twice daily for five days. Scrub typhus complicating pregnancy led to maternal mortality in one patient. It resulted in one preterm delivery, one intrauterine fetal death, and rest three were delivered at term with good perinatal outcome. Conclusion: Scrub typhus is common in endemic areas like Uttarakhand, India. It has a poor fetal outcome. If diagnosed early and treatment started, maternal and fetal prognosis can be favorable. As large case series are unavailable in literature, it is difficult to predict the course of disease which at times may be fulminant. |
| first_indexed | 2024-04-24T19:39:42Z |
| format | Article |
| id | doaj.art-6209047c73cd4f04bf137f8a842aef85 |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-04-24T19:39:42Z |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-6209047c73cd4f04bf137f8a842aef852024-03-25T11:16:14ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632024-01-0113276476710.4103/jfmpc.jfmpc_1347_23Scrub typhus in pregnancy - A threat to maternal and fetal outcomeAnupama BahadurRajlaxmi MundhraAnjali PathakMukesh KumarShri Ram RundlaGayatri SureshBackground and Objectives: Scrub typhus is an acute febrile illness transmitted by the bite of trombiculid mite in the larval stage. Scrub typhus is rare in pregnancy and there is paucity of data on the clinical outcome of scrub typhus during pregnancy. Material and Methods: We present five cases of scrub typhus complicating pregnancy who were admitted in the obstetric ward at AIIMS Rishikesh, India during the antenatal period for management. Results: The first patient presented at term pregnancy in semiconscious state while the rest were preterm between 31 and 34 weeks period of gestation. The age at presentation was 21–31 years. All five had febrile illness of >5 days' duration along with cough. Fever investigations like blood culture, peripheral smear for malarial parasite, dengue serology, widal test, and urine culture were negative. Serology for scrub typhus was positive in all. Once diagnosis was confirmed for scrub typhus, patients were given the drug of choice azithromycin 500 mg twice daily for five days. Scrub typhus complicating pregnancy led to maternal mortality in one patient. It resulted in one preterm delivery, one intrauterine fetal death, and rest three were delivered at term with good perinatal outcome. Conclusion: Scrub typhus is common in endemic areas like Uttarakhand, India. It has a poor fetal outcome. If diagnosed early and treatment started, maternal and fetal prognosis can be favorable. As large case series are unavailable in literature, it is difficult to predict the course of disease which at times may be fulminant.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2024;volume=13;issue=2;spage=764;epage=767;aulast=Bahadurpregnancy with febrile illnesspregnancy with infectious diseasesscrub typhus |
| spellingShingle | Anupama Bahadur Rajlaxmi Mundhra Anjali Pathak Mukesh Kumar Shri Ram Rundla Gayatri Suresh Scrub typhus in pregnancy - A threat to maternal and fetal outcome Journal of Family Medicine and Primary Care pregnancy with febrile illness pregnancy with infectious diseases scrub typhus |
| title | Scrub typhus in pregnancy - A threat to maternal and fetal outcome |
| title_full | Scrub typhus in pregnancy - A threat to maternal and fetal outcome |
| title_fullStr | Scrub typhus in pregnancy - A threat to maternal and fetal outcome |
| title_full_unstemmed | Scrub typhus in pregnancy - A threat to maternal and fetal outcome |
| title_short | Scrub typhus in pregnancy - A threat to maternal and fetal outcome |
| title_sort | scrub typhus in pregnancy a threat to maternal and fetal outcome |
| topic | pregnancy with febrile illness pregnancy with infectious diseases scrub typhus |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2024;volume=13;issue=2;spage=764;epage=767;aulast=Bahadur |
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