Continuously Tunable Ca2+ Regulation of RNA-Edited CaV1.3 Channels
CaV1.3 ion channels are dominant Ca2+ portals into pacemaking neurons, residing at the epicenter of brain rhythmicity and neurodegeneration. Negative Ca2+ feedback regulation of CaV1.3 channels (CDI) is therefore critical for Ca2+ homeostasis. Intriguingly, nearly half the CaV1.3 transcripts in the...
Main Authors: | Hojjat Bazzazi, Manu Ben Johny, Paul J. Adams, Tuck Wah Soong, David T. Yue |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-10-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124713005147 |
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