Comparative Evaluation of the Antioxidant and Anti-Alzheimer’s Disease Potential of Coumestrol and Puerarol Isolated from Pueraria lobata Using Molecular Modeling Studies

Comparative Evaluation of the Antioxidant and Anti-Alzheimer’s Disease Potential of Coumestrol and Puerarol Isolated from Pueraria lobata Using Molecular Modeling Studies

The current study assesses the antioxidant effects of two similar isoflavonoids isolated from Pueraria lobata, coumestrol and puerarol, along with the cholinergic and amyloid-cascade pathways to mitigate Alzheimer’s disease (AD). Antioxidant activity was evaluated via 1,1-diphenyl-2-picryhydrazyl (D...

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Bibliographic Details
Main Authors: Prashamsa Koirala, Su Hui Seong, Hyun Ah Jung, Jae Sue Choi
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Molecules
Subjects:
cholinesterase
BACE1
molecular docking
kinetics
Alzheimer’s disease
Online Access:http://www.mdpi.com/1420-3049/23/4/785

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http://www.mdpi.com/1420-3049/23/4/785

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