Multi-finger receptive field properties in primary somatosensory cortex: A revised account of the spatiotemporal integration functions of area 3b
Summary: The leading view in the somatosensory system indicates that area 3b serves as a cortical relay site that primarily encodes (cutaneous) tactile features limited to individual digits. Our recent work argues against this model by showing that area 3b cells can integrate both cutaneous and prop...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Cell Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723001870 |
| _version_ | 1827999033729220608 |
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| author | Natalie K. Trzcinski Steven S. Hsiao Charles E. Connor Manuel Gomez-Ramirez |
| author_facet | Natalie K. Trzcinski Steven S. Hsiao Charles E. Connor Manuel Gomez-Ramirez |
| author_sort | Natalie K. Trzcinski |
| collection | DOAJ |
| description | Summary: The leading view in the somatosensory system indicates that area 3b serves as a cortical relay site that primarily encodes (cutaneous) tactile features limited to individual digits. Our recent work argues against this model by showing that area 3b cells can integrate both cutaneous and proprioceptive information from the hand. Here, we further test the validity of this model by studying multi-digit (MD) integration properties in area 3b. In contrast to the prevailing view, we show that most cells in area 3b have a receptive field (RF) that extends to multiple digits, with the size of the RF (i.e., the number of responsive digits) increasing across time. Further, we show that MD cells’ orientation angle preference is highly correlated across digits. Taken together, these data show that area 3b plays a larger role in generating neural representations of tactile objects, as opposed to just being a “feature detector” relay site. |
| first_indexed | 2024-04-10T05:52:52Z |
| format | Article |
| id | doaj.art-621293a0fdce418b89b9cf7daa9925d7 |
| institution | Directory Open Access Journal |
| issn | 2211-1247 |
| language | English |
| last_indexed | 2024-04-10T05:52:52Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cell Reports |
| spelling | doaj.art-621293a0fdce418b89b9cf7daa9925d72023-03-04T04:22:55ZengElsevierCell Reports2211-12472023-03-01423112176Multi-finger receptive field properties in primary somatosensory cortex: A revised account of the spatiotemporal integration functions of area 3bNatalie K. Trzcinski0Steven S. Hsiao1Charles E. Connor2Manuel Gomez-Ramirez3National Institute of Neurological Disorders & Stroke, National Institutes of Health, Bethesda, MD, USAThe Zanvyl Krieger Mind/Brain Institute, The Johns Hopkins University, Baltimore, MD 21218, USA; The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins School of Medicine, Baltimore, MD 21218, USAThe Zanvyl Krieger Mind/Brain Institute, The Johns Hopkins University, Baltimore, MD 21218, USA; The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins School of Medicine, Baltimore, MD 21218, USADepartment of Brain and Cognitive Sciences, University of Rochester, Rochester, NY 14642, USA; Corresponding authorSummary: The leading view in the somatosensory system indicates that area 3b serves as a cortical relay site that primarily encodes (cutaneous) tactile features limited to individual digits. Our recent work argues against this model by showing that area 3b cells can integrate both cutaneous and proprioceptive information from the hand. Here, we further test the validity of this model by studying multi-digit (MD) integration properties in area 3b. In contrast to the prevailing view, we show that most cells in area 3b have a receptive field (RF) that extends to multiple digits, with the size of the RF (i.e., the number of responsive digits) increasing across time. Further, we show that MD cells’ orientation angle preference is highly correlated across digits. Taken together, these data show that area 3b plays a larger role in generating neural representations of tactile objects, as opposed to just being a “feature detector” relay site.http://www.sciencedirect.com/science/article/pii/S2211124723001870CP: Neuroscience |
| spellingShingle | Natalie K. Trzcinski Steven S. Hsiao Charles E. Connor Manuel Gomez-Ramirez Multi-finger receptive field properties in primary somatosensory cortex: A revised account of the spatiotemporal integration functions of area 3b Cell Reports CP: Neuroscience |
| title | Multi-finger receptive field properties in primary somatosensory cortex: A revised account of the spatiotemporal integration functions of area 3b |
| title_full | Multi-finger receptive field properties in primary somatosensory cortex: A revised account of the spatiotemporal integration functions of area 3b |
| title_fullStr | Multi-finger receptive field properties in primary somatosensory cortex: A revised account of the spatiotemporal integration functions of area 3b |
| title_full_unstemmed | Multi-finger receptive field properties in primary somatosensory cortex: A revised account of the spatiotemporal integration functions of area 3b |
| title_short | Multi-finger receptive field properties in primary somatosensory cortex: A revised account of the spatiotemporal integration functions of area 3b |
| title_sort | multi finger receptive field properties in primary somatosensory cortex a revised account of the spatiotemporal integration functions of area 3b |
| topic | CP: Neuroscience |
| url | http://www.sciencedirect.com/science/article/pii/S2211124723001870 |
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