Expected Additional Protection Rate against Omicron COVID-19 Infection and Death for the Fifth Dose of COVID-19 Vaccine: An Appraisal from an Endemic Area in Indochina

Objective: COVID-19 is still a global emergency with no effective treatment. Vaccination is the greatest option for disaster management. COVID-19 vaccination is now universally acknowledged as an effective primary COVID-19 preventive strategy. In the case of the introduction of a new strain, as well...

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Main Authors: Rujittika Mungmunpuntipantip, Viroj Wiwanitkit
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Journal of the Scientific Society
Subjects:
Online Access:http://www.jscisociety.com/article.asp?issn=0974-5009;year=2024;volume=51;issue=1;spage=72;epage=75;aulast=Mungmunpuntipantip
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author Rujittika Mungmunpuntipantip
Viroj Wiwanitkit
author_facet Rujittika Mungmunpuntipantip
Viroj Wiwanitkit
author_sort Rujittika Mungmunpuntipantip
collection DOAJ
description Objective: COVID-19 is still a global emergency with no effective treatment. Vaccination is the greatest option for disaster management. COVID-19 vaccination is now universally acknowledged as an effective primary COVID-19 preventive strategy. In the case of the introduction of a new strain, as well as the likely loss of public immunity following routine mass vaccination, some scientists are recommending a fifth dosage vaccine. Because the efficacy of the fifth vaccine dose is unknown, any investigation into its efficacy is intriguing. Materials and Methods: To evaluate an additional protection rate against omicron COVID-19 infection and death resulting from a fifth dose of COVID-19 vaccine, the authors of this study used a clinical model technique. Results: According to simulations, the fifth immunization dose can still enhance immunity and provide additional protection against omicron COVID-19 infection. Despite this, the fifth immunisation dose can still enhance immunity while providing no additional protection against omicron COVID-19 mortality. Conclusions: There is no additional benefit in terms of avoiding omicron COVID-19 death because just four vaccination doses are required to protect against mortality.
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spelling doaj.art-6212b0dc4a594e219ea537f25b0b03b52024-03-25T12:58:35ZengWolters Kluwer Medknow PublicationsJournal of the Scientific Society0974-50092024-01-01511727510.4103/jss.jss_277_22Expected Additional Protection Rate against Omicron COVID-19 Infection and Death for the Fifth Dose of COVID-19 Vaccine: An Appraisal from an Endemic Area in IndochinaRujittika MungmunpuntipantipViroj WiwanitkitObjective: COVID-19 is still a global emergency with no effective treatment. Vaccination is the greatest option for disaster management. COVID-19 vaccination is now universally acknowledged as an effective primary COVID-19 preventive strategy. In the case of the introduction of a new strain, as well as the likely loss of public immunity following routine mass vaccination, some scientists are recommending a fifth dosage vaccine. Because the efficacy of the fifth vaccine dose is unknown, any investigation into its efficacy is intriguing. Materials and Methods: To evaluate an additional protection rate against omicron COVID-19 infection and death resulting from a fifth dose of COVID-19 vaccine, the authors of this study used a clinical model technique. Results: According to simulations, the fifth immunization dose can still enhance immunity and provide additional protection against omicron COVID-19 infection. Despite this, the fifth immunisation dose can still enhance immunity while providing no additional protection against omicron COVID-19 mortality. Conclusions: There is no additional benefit in terms of avoiding omicron COVID-19 death because just four vaccination doses are required to protect against mortality.http://www.jscisociety.com/article.asp?issn=0974-5009;year=2024;volume=51;issue=1;spage=72;epage=75;aulast=Mungmunpuntipantipcovid-19fifth doseprotectionvaccine
spellingShingle Rujittika Mungmunpuntipantip
Viroj Wiwanitkit
Expected Additional Protection Rate against Omicron COVID-19 Infection and Death for the Fifth Dose of COVID-19 Vaccine: An Appraisal from an Endemic Area in Indochina
Journal of the Scientific Society
covid-19
fifth dose
protection
vaccine
title Expected Additional Protection Rate against Omicron COVID-19 Infection and Death for the Fifth Dose of COVID-19 Vaccine: An Appraisal from an Endemic Area in Indochina
title_full Expected Additional Protection Rate against Omicron COVID-19 Infection and Death for the Fifth Dose of COVID-19 Vaccine: An Appraisal from an Endemic Area in Indochina
title_fullStr Expected Additional Protection Rate against Omicron COVID-19 Infection and Death for the Fifth Dose of COVID-19 Vaccine: An Appraisal from an Endemic Area in Indochina
title_full_unstemmed Expected Additional Protection Rate against Omicron COVID-19 Infection and Death for the Fifth Dose of COVID-19 Vaccine: An Appraisal from an Endemic Area in Indochina
title_short Expected Additional Protection Rate against Omicron COVID-19 Infection and Death for the Fifth Dose of COVID-19 Vaccine: An Appraisal from an Endemic Area in Indochina
title_sort expected additional protection rate against omicron covid 19 infection and death for the fifth dose of covid 19 vaccine an appraisal from an endemic area in indochina
topic covid-19
fifth dose
protection
vaccine
url http://www.jscisociety.com/article.asp?issn=0974-5009;year=2024;volume=51;issue=1;spage=72;epage=75;aulast=Mungmunpuntipantip
work_keys_str_mv AT rujittikamungmunpuntipantip expectedadditionalprotectionrateagainstomicroncovid19infectionanddeathforthefifthdoseofcovid19vaccineanappraisalfromanendemicareainindochina
AT virojwiwanitkit expectedadditionalprotectionrateagainstomicroncovid19infectionanddeathforthefifthdoseofcovid19vaccineanappraisalfromanendemicareainindochina