Selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomography
Hepatocellular carcinoma (HCC) of the liver is the third most common cause of cancer-related deaths in the world. Only one-third of patients with HCC are suitable candidates for hepatic resection. Transarterial chemoembolization (TACE) is performed in unresectable HCC. Drug-eluting beads (DEB) TACE...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2012-10-01
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| Series: | Indian Journal of Radiology and Imaging |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/0971-3026.111472 |
| _version_ | 1819121006079377408 |
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| author | Naveen Kalra Divyesh Mahajan Yogesh Chawla N Khandelwal |
| author_facet | Naveen Kalra Divyesh Mahajan Yogesh Chawla N Khandelwal |
| author_sort | Naveen Kalra |
| collection | DOAJ |
| description | Hepatocellular carcinoma (HCC) of the liver is the third most common cause of cancer-related deaths in the world. Only one-third of patients with HCC are suitable candidates for hepatic resection. Transarterial chemoembolization (TACE) is performed in unresectable HCC. Drug-eluting beads (DEB) TACE is a modification of TACE, in which doxorubicin beads are used as embolizing material.These beads deliver the drug and embolize the vessels; however, it carries the risk of non-target embolization and it is difficult in cases with absent arterial blush on digital subtraction angiography (DSA). This is resolved using C-arm cone-beam computed tomography in the DSA suite. It identifies the tumor-feeding vessels, their area of supply, and differentiates between tumor and normal liver parenchyma. In addition, it is very useful in the embolization of hypovascular HCC. It helps and guides the radiologist in performing TACE effectively and also prevents non-target embolization of normal liver parenchyma. |
| first_indexed | 2024-12-22T06:29:41Z |
| format | Article |
| id | doaj.art-6216595e17db4074903bc5bc9aa7c4b8 |
| institution | Directory Open Access Journal |
| issn | 0971-3026 1998-3808 |
| language | English |
| last_indexed | 2024-12-22T06:29:41Z |
| publishDate | 2012-10-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Radiology and Imaging |
| spelling | doaj.art-6216595e17db4074903bc5bc9aa7c4b82022-12-21T18:35:45ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Radiology and Imaging0971-30261998-38082012-10-01220425425610.4103/0971-3026.111472Selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomographyNaveen Kalra0Divyesh Mahajan1Yogesh Chawla2N Khandelwal3Department of Radiodiagnosis, Post-graduate Institute of Medical Education and Research, ChandigarhDepartment of Radiodiagnosis, Post-graduate Institute of Medical Education and Research, ChandigarhDepartment of Hepatology, Post-graduate Institute of Medical Education and Research, ChandigarhDepartment of Radiodiagnosis, Post-graduate Institute of Medical Education and Research, ChandigarhHepatocellular carcinoma (HCC) of the liver is the third most common cause of cancer-related deaths in the world. Only one-third of patients with HCC are suitable candidates for hepatic resection. Transarterial chemoembolization (TACE) is performed in unresectable HCC. Drug-eluting beads (DEB) TACE is a modification of TACE, in which doxorubicin beads are used as embolizing material.These beads deliver the drug and embolize the vessels; however, it carries the risk of non-target embolization and it is difficult in cases with absent arterial blush on digital subtraction angiography (DSA). This is resolved using C-arm cone-beam computed tomography in the DSA suite. It identifies the tumor-feeding vessels, their area of supply, and differentiates between tumor and normal liver parenchyma. In addition, it is very useful in the embolization of hypovascular HCC. It helps and guides the radiologist in performing TACE effectively and also prevents non-target embolization of normal liver parenchyma.http://www.thieme-connect.de/DOI/DOI?10.4103/0971-3026.111472cone-beam computed tomographyhepatocellular carcinomatransarterial chemoembolization |
| spellingShingle | Naveen Kalra Divyesh Mahajan Yogesh Chawla N Khandelwal Selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomography Indian Journal of Radiology and Imaging cone-beam computed tomography hepatocellular carcinoma transarterial chemoembolization |
| title | Selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomography |
| title_full | Selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomography |
| title_fullStr | Selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomography |
| title_full_unstemmed | Selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomography |
| title_short | Selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomography |
| title_sort | selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomography |
| topic | cone-beam computed tomography hepatocellular carcinoma transarterial chemoembolization |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/0971-3026.111472 |
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