An enemy in shadows—Mycoplasma hominis septic arthritis and iliopsoas abscess: Case report and review of the literature
Mycoplasma hominis (M. hominis) is fastidious and difficult to grow bacteria with the ability to colonize the genitourinary and respiratory tracts. Infrequently can cause a variety of genitourinary tract infections, pregnancy complications, and neonatal diseases. M. hominis rarely reported to cause...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S221425092100216X |
| _version_ | 1818352764003024896 |
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| author | Gawahir A. Ali Wael Goravey Abdulrahman Hamad Emad B. Ibrahim Mohamed R. Hasan Muna Al Maslamani Hussam Al Soub |
| author_facet | Gawahir A. Ali Wael Goravey Abdulrahman Hamad Emad B. Ibrahim Mohamed R. Hasan Muna Al Maslamani Hussam Al Soub |
| author_sort | Gawahir A. Ali |
| collection | DOAJ |
| description | Mycoplasma hominis (M. hominis) is fastidious and difficult to grow bacteria with the ability to colonize the genitourinary and respiratory tracts. Infrequently can cause a variety of genitourinary tract infections, pregnancy complications, and neonatal diseases. M. hominis rarely reported to cause extragenital infections and seldomly native joint septic arthritis particularly in immunocompromised hosts, raising diagnostic challenges and is often associated with delayed diagnosis and high morbidity and mortality. We report the case of a 30-year-old patient who developed M. hominis native left hip septic arthritis with iliopsoas abscess after receiving rituximab for newly diagnosed thrombotic thrombocytopenic purpura (TTP). The diagnosis of M. hominis hip septic arthritis with iliopsoas involvement was confirmed following repeated joint and abscess aspiration and identification of the organism with the aid of culture and specific Polymerase chain reaction (PCR). The patient was subsequently treated with a prolonged course of antibiotics targeting the organism with a favorable outcome. The clinical presentations, assessment, and management of this rare entity of M. hominis related extragenital infections are outlined. In addition, the literature on similar cases was reviewed to raise awareness and avoid devastating consequences. |
| first_indexed | 2024-12-13T18:58:49Z |
| format | Article |
| id | doaj.art-62190a01d3454c369f717840e5dbd03c |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-12-13T18:58:49Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-62190a01d3454c369f717840e5dbd03c2022-12-21T23:34:44ZengElsevierIDCases2214-25092021-01-0126e01260An enemy in shadows—Mycoplasma hominis septic arthritis and iliopsoas abscess: Case report and review of the literatureGawahir A. Ali0Wael Goravey1Abdulrahman Hamad2Emad B. Ibrahim3Mohamed R. Hasan4Muna Al Maslamani5Hussam Al Soub6Department of Infectious Diseases, Communicable Diseases Centre, Hamad Medical Corporation, Doha, Qatar; Correspondence to: Department of Infectious Diseases, Hamad Medical Corporation, Doha, Qatar.Department of Infectious Diseases, Communicable Diseases Centre, Hamad Medical Corporation, Doha, QatarDepartment of Internal Medicine, Hamad Medical Corporation, Doha, QatarDepartment of Laboratory Medicine and Pathology, HMC, Doha and Qatar University, Biomedical Research Centre, Doha, QatarDepartment of Pathology, Sidra Medicine, Doha, QatarDepartment of Infectious Diseases, Communicable Diseases Centre, Hamad Medical Corporation, Doha, QatarDepartment of Infectious Diseases, Communicable Diseases Centre, Hamad Medical Corporation, Doha, QatarMycoplasma hominis (M. hominis) is fastidious and difficult to grow bacteria with the ability to colonize the genitourinary and respiratory tracts. Infrequently can cause a variety of genitourinary tract infections, pregnancy complications, and neonatal diseases. M. hominis rarely reported to cause extragenital infections and seldomly native joint septic arthritis particularly in immunocompromised hosts, raising diagnostic challenges and is often associated with delayed diagnosis and high morbidity and mortality. We report the case of a 30-year-old patient who developed M. hominis native left hip septic arthritis with iliopsoas abscess after receiving rituximab for newly diagnosed thrombotic thrombocytopenic purpura (TTP). The diagnosis of M. hominis hip septic arthritis with iliopsoas involvement was confirmed following repeated joint and abscess aspiration and identification of the organism with the aid of culture and specific Polymerase chain reaction (PCR). The patient was subsequently treated with a prolonged course of antibiotics targeting the organism with a favorable outcome. The clinical presentations, assessment, and management of this rare entity of M. hominis related extragenital infections are outlined. In addition, the literature on similar cases was reviewed to raise awareness and avoid devastating consequences.http://www.sciencedirect.com/science/article/pii/S221425092100216XMycoplasma hominisseptic arthritisrituximabPCRdoxycycline |
| spellingShingle | Gawahir A. Ali Wael Goravey Abdulrahman Hamad Emad B. Ibrahim Mohamed R. Hasan Muna Al Maslamani Hussam Al Soub An enemy in shadows—Mycoplasma hominis septic arthritis and iliopsoas abscess: Case report and review of the literature IDCases Mycoplasma hominis septic arthritis rituximab PCR doxycycline |
| title | An enemy in shadows—Mycoplasma hominis septic arthritis and iliopsoas abscess: Case report and review of the literature |
| title_full | An enemy in shadows—Mycoplasma hominis septic arthritis and iliopsoas abscess: Case report and review of the literature |
| title_fullStr | An enemy in shadows—Mycoplasma hominis septic arthritis and iliopsoas abscess: Case report and review of the literature |
| title_full_unstemmed | An enemy in shadows—Mycoplasma hominis septic arthritis and iliopsoas abscess: Case report and review of the literature |
| title_short | An enemy in shadows—Mycoplasma hominis septic arthritis and iliopsoas abscess: Case report and review of the literature |
| title_sort | enemy in shadows mycoplasma hominis septic arthritis and iliopsoas abscess case report and review of the literature |
| topic | Mycoplasma hominis septic arthritis rituximab PCR doxycycline |
| url | http://www.sciencedirect.com/science/article/pii/S221425092100216X |
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