Complex treatment of vaginal dysbiosis in women with recurrent miscarriage in assisted reproductive treatment (ART)
The article presents literature data on modern approaches to diagnosis and treatment of vaginal dysbiosis caused by fungi of the genus Candida and personal data on the effectiveness of vaginal dysbiosis treatment in women with recurrent miscarriage occurring in ART cycles by combined local therapy w...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2017-06-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/24042 |
| _version_ | 1811339435189469184 |
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| author | O. M. Nosenko K. P. Golovatyuk |
| author_facet | O. M. Nosenko K. P. Golovatyuk |
| author_sort | O. M. Nosenko |
| collection | DOAJ |
| description | The article presents literature data on modern approaches to diagnosis and treatment of vaginal dysbiosis caused by fungi of the genus Candida and personal data on the effectiveness of vaginal dysbiosis treatment in women with recurrent miscarriage occurring in ART cycles by combined local therapy with sertaconazole and povidone-iodine. 240 patients of reproductive age with habitual miscarriage of pregnancy after ART and 30 conditionally healthy fertile women were examined. The state of vaginal microbiota was studied using PCR and culture. It were carried out a species identification of the fungi of the genus Candida and their susceptibility to antimycotics. It has been established that among women with a recurrent miscarriage after cycles of ART that repeatedly receive antibacterial therapy in preparation in the ART cycles and after abortion, in the vaginal microbiota Vaginal dysbiosis was observed in 54.58% of the cases, in which increased colonization by bacterial-fungal associates was noted in 67.18% of individuals. The authors prove that Sertaconazole in combination with povidone iodine is a highly effective regimen of vaginal microbiota normalization in patients with ART with a recurrent miscarriage, even in individuals with the development of cross-resistance to antimycotic therapy.
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| first_indexed | 2024-04-13T18:26:34Z |
| format | Article |
| id | doaj.art-621e6a33c21249b7b586d23909584ee8 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-04-13T18:26:34Z |
| publishDate | 2017-06-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-621e6a33c21249b7b586d23909584ee82022-12-22T02:35:14ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-06-0176Complex treatment of vaginal dysbiosis in women with recurrent miscarriage in assisted reproductive treatment (ART)O. M. Nosenko0K. P. Golovatyuk1Odessa National Medical UniversityOdessa National Medical UniversityThe article presents literature data on modern approaches to diagnosis and treatment of vaginal dysbiosis caused by fungi of the genus Candida and personal data on the effectiveness of vaginal dysbiosis treatment in women with recurrent miscarriage occurring in ART cycles by combined local therapy with sertaconazole and povidone-iodine. 240 patients of reproductive age with habitual miscarriage of pregnancy after ART and 30 conditionally healthy fertile women were examined. The state of vaginal microbiota was studied using PCR and culture. It were carried out a species identification of the fungi of the genus Candida and their susceptibility to antimycotics. It has been established that among women with a recurrent miscarriage after cycles of ART that repeatedly receive antibacterial therapy in preparation in the ART cycles and after abortion, in the vaginal microbiota Vaginal dysbiosis was observed in 54.58% of the cases, in which increased colonization by bacterial-fungal associates was noted in 67.18% of individuals. The authors prove that Sertaconazole in combination with povidone iodine is a highly effective regimen of vaginal microbiota normalization in patients with ART with a recurrent miscarriage, even in individuals with the development of cross-resistance to antimycotic therapy. https://apcz.umk.pl/JEHS/article/view/24042vaginal dysbiosiscandidiasisARTmiscarriagesertaconazolepovidone-iodine. |
| spellingShingle | O. M. Nosenko K. P. Golovatyuk Complex treatment of vaginal dysbiosis in women with recurrent miscarriage in assisted reproductive treatment (ART) Journal of Education, Health and Sport vaginal dysbiosis candidiasis ART miscarriage sertaconazole povidone-iodine. |
| title | Complex treatment of vaginal dysbiosis in women with recurrent miscarriage in assisted reproductive treatment (ART) |
| title_full | Complex treatment of vaginal dysbiosis in women with recurrent miscarriage in assisted reproductive treatment (ART) |
| title_fullStr | Complex treatment of vaginal dysbiosis in women with recurrent miscarriage in assisted reproductive treatment (ART) |
| title_full_unstemmed | Complex treatment of vaginal dysbiosis in women with recurrent miscarriage in assisted reproductive treatment (ART) |
| title_short | Complex treatment of vaginal dysbiosis in women with recurrent miscarriage in assisted reproductive treatment (ART) |
| title_sort | complex treatment of vaginal dysbiosis in women with recurrent miscarriage in assisted reproductive treatment art |
| topic | vaginal dysbiosis candidiasis ART miscarriage sertaconazole povidone-iodine. |
| url | https://apcz.umk.pl/JEHS/article/view/24042 |
| work_keys_str_mv | AT omnosenko complextreatmentofvaginaldysbiosisinwomenwithrecurrentmiscarriageinassistedreproductivetreatmentart AT kpgolovatyuk complextreatmentofvaginaldysbiosisinwomenwithrecurrentmiscarriageinassistedreproductivetreatmentart |