The unfolded protein response components IRE1α and XBP1 promote human coronavirus infection

The unfolded protein response components IRE1α and XBP1 promote human coronavirus infection

ABSTRACT The cellular processes that support human coronavirus replication and contribute to the pathogenesis of severe disease remain incompletely understood. Many viruses, including coronaviruses, cause endoplasmic reticulum (ER) stress during infection. IRE1α is a component of the cellular respon...

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Bibliographic Details
Main Authors: Jessica M. Oda, Andreas B. den Hartigh, Shoen M. Jackson, Ana R. Tronco, Susan L. Fink
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mBio
Subjects:
coronavirus
unfolded protein response
ER stress
SARS-CoV-2
HCoV-OC43
endoplasmic reticulum
Online Access:https://journals.asm.org/doi/10.1128/mbio.00540-23

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